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Circulating endothelial progenitor cells: a new approach to anti-aging medicine?

Overview of attention for article published in Journal of Translational Medicine, December 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

twitter
13 tweeters
weibo
1 weibo user
facebook
1 Facebook page
video
2 video uploaders

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
99 Mendeley
citeulike
1 CiteULike
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Title
Circulating endothelial progenitor cells: a new approach to anti-aging medicine?
Published in
Journal of Translational Medicine, December 2009
DOI 10.1186/1479-5876-7-106
Pubmed ID
Authors

Nina A Mikirova, James A Jackson, Ron Hunninghake, Julian Kenyon, Kyle WH Chan, Cathy A Swindlehurst, Boris Minev, Amit N Patel, Michael P Murphy, Leonard Smith, Doru T Alexandrescu, Thomas E Ichim, Neil H Riordan

Abstract

Endothelial dysfunction is associated with major causes of morbidity and mortality, as well as numerous age-related conditions. The possibility of preserving or even rejuvenating endothelial function offers a potent means of preventing/treating some of the most fearful aspects of aging such as loss of mental, cardiovascular, and sexual function.Endothelial precursor cells (EPC) provide a continual source of replenishment for damaged or senescent blood vessels. In this review we discuss the biological relevance of circulating EPC in a variety of pathologies in order to build the case that these cells act as an endogenous mechanism of regeneration. Factors controlling EPC mobilization, migration, and function, as well as therapeutic interventions based on mobilization of EPC will be reviewed. We conclude by discussing several clinically-relevant approaches to EPC mobilization and provide preliminary data on a food supplement, Stem-Kine, which enhanced EPC mobilization in human subjects.

Twitter Demographics

The data shown below were collected from the profiles of 13 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Indonesia 1 1%
Germany 1 1%
Brazil 1 1%
Unknown 94 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 27 27%
Student > Ph. D. Student 10 10%
Other 9 9%
Student > Bachelor 9 9%
Professor > Associate Professor 8 8%
Other 27 27%
Unknown 9 9%
Readers by discipline Count As %
Medicine and Dentistry 42 42%
Agricultural and Biological Sciences 19 19%
Psychology 5 5%
Nursing and Health Professions 3 3%
Biochemistry, Genetics and Molecular Biology 3 3%
Other 12 12%
Unknown 15 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2017.
All research outputs
#2,043,179
of 21,326,488 outputs
Outputs from Journal of Translational Medicine
#313
of 3,676 outputs
Outputs of similar age
#11,568
of 133,428 outputs
Outputs of similar age from Journal of Translational Medicine
#11
of 123 outputs
Altmetric has tracked 21,326,488 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,676 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 133,428 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.