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Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?

Overview of attention for article published in Arthritis Research & Therapy, October 2011
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Title
Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?
Published in
Arthritis Research & Therapy, October 2011
DOI 10.1186/ar3505
Pubmed ID
Authors

Diederik PC De Rooy, Annemiek Willemze, Bart Mertens, Tom WJ Huizinga, Annette HM Van der Helm-van Mil

Abstract

Studies investigating genetic risk factors for susceptibility to rheumatoid arthritis (RA) studied anti-citrullinated peptide antibody (CCP)-positive RA more frequently than anti-CCP-negative RA. One of the reasons for this is the perception that anti-CCP-negative RA may include patients that fulfilled criteria for RA but belong to a wide range of diagnoses. We aimed to evaluate the validity of this notion and explored whether clinical subphenotypes can be discerned within anti-CCP-negative RA.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
United States 1 4%
Colombia 1 4%
Italy 1 4%
Unknown 24 86%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 18%
Researcher 4 14%
Other 3 11%
Student > Postgraduate 3 11%
Student > Bachelor 2 7%
Other 8 29%
Unknown 3 11%
Readers by discipline Count As %
Medicine and Dentistry 12 43%
Mathematics 2 7%
Engineering 2 7%
Immunology and Microbiology 2 7%
Agricultural and Biological Sciences 2 7%
Other 3 11%
Unknown 5 18%