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A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz’s disease

Overview of attention for article published in World Journal of Surgical Oncology, July 2015
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Title
A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz’s disease
Published in
World Journal of Surgical Oncology, July 2015
DOI 10.1186/s12957-015-0644-0
Pubmed ID
Authors

Yoshikazu Hayashi, Masafumi Moriyama, Takashi Maehara, Yuichi Goto, Shintaro Kawano, Miho Ohta, Akihiko Tanaka, Sachiko Furukawa, Jun-Nosuke Hayashida, Tamotsu Kiyoshima, Mayumi Shimizu, Toru Chikui, Seiji Nakamura

Abstract

Mantle cell lymphoma (MCL) is a relatively uncommon type of non-Hodgkin lymphoma. It develops in the outer edge of a lymph node called the mantle zone. In contrast, IgG4-related dacryoadenitis and sialoadenitis (IgG4-DS) is characterized by elevated serum IgG4 and persistent bilateral enlargement of lacrimal glands (LGs) and salivary glands (SGs), with infiltration of IgG4-positive plasma cells. Recent studies indicated the importance of differentiation between IgG4-DS and malignant lymphoma. An 82-year-old man was suspected of IgG4-DS because of a high serum IgG level (2174 mg/dL) and bilateral swelling of LGs and SGs. Lip biopsy and fine needle biopsy of submandibular gland were performed, and subsequently, MCL was diagnosed through the histopathological findings. MCL most commonly occurs in the Waldeyer ring, but rarely in the stomach, spleen, skin, LG, and SG. We report an unusual case of MCL involving LGs and SGs mimicking IgG4-DS, which suggests that IgG4 testing may be useful in the differentiation of IgG4-DS in the presence of bilateral swelling of LGs or SGs.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Other 5 21%
Student > Ph. D. Student 2 8%
Student > Postgraduate 2 8%
Professor > Associate Professor 2 8%
Student > Bachelor 1 4%
Other 5 21%
Unknown 7 29%
Readers by discipline Count As %
Medicine and Dentistry 10 42%
Unspecified 1 4%
Neuroscience 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Unknown 11 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2015.
All research outputs
#18,418,919
of 22,817,213 outputs
Outputs from World Journal of Surgical Oncology
#1,011
of 2,043 outputs
Outputs of similar age
#189,156
of 263,272 outputs
Outputs of similar age from World Journal of Surgical Oncology
#29
of 50 outputs
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