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Next-generation sequencing to guide cancer therapy

Overview of attention for article published in Genome Medicine, July 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)

Mentioned by

news
7 news outlets
policy
1 policy source
twitter
42 tweeters
patent
2 patents
facebook
2 Facebook pages

Citations

dimensions_citation
203 Dimensions

Readers on

mendeley
445 Mendeley
citeulike
3 CiteULike
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Title
Next-generation sequencing to guide cancer therapy
Published in
Genome Medicine, July 2015
DOI 10.1186/s13073-015-0203-x
Pubmed ID
Authors

Jeffrey Gagan, Eliezer M. Van Allen

Abstract

As a result of multiple technological and practical advances, high-throughput sequencing, known more commonly as "next-generation" sequencing (NGS), can now be incorporated into standard clinical practice. Whereas early protocols relied on samples that were harvested outside of typical clinical pathology workflows, standard formalin-fixed, paraffin-embedded specimens can more regularly be used as starting materials for NGS. Furthermore, protocols for the analysis and interpretation of NGS data, as well as knowledge bases, are being amassed, allowing clinicians to act more easily on genomic information at the point of care for patients. In parallel, new therapies that target somatically mutated genes identified through clinical NGS are gaining US Food and Drug Administration (FDA) approval, and novel clinical trial designs are emerging in which genetic identifiers are given equal weight to histology. For clinical oncology providers, understanding the potential and the limitations of DNA sequencing will be crucial for providing genomically driven care in this era of precision medicine.

Twitter Demographics

The data shown below were collected from the profiles of 42 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 445 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 <1%
Canada 2 <1%
Netherlands 1 <1%
United Kingdom 1 <1%
India 1 <1%
Brazil 1 <1%
Mexico 1 <1%
Sri Lanka 1 <1%
China 1 <1%
Other 1 <1%
Unknown 432 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 88 20%
Student > Ph. D. Student 81 18%
Student > Master 53 12%
Student > Bachelor 42 9%
Other 35 8%
Other 76 17%
Unknown 70 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 113 25%
Agricultural and Biological Sciences 106 24%
Medicine and Dentistry 88 20%
Computer Science 12 3%
Engineering 11 2%
Other 33 7%
Unknown 82 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 85. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2022.
All research outputs
#373,096
of 21,240,621 outputs
Outputs from Genome Medicine
#64
of 1,351 outputs
Outputs of similar age
#4,844
of 248,528 outputs
Outputs of similar age from Genome Medicine
#1
of 3 outputs
Altmetric has tracked 21,240,621 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,351 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.8. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 248,528 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them