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Impact of the biological definition of Alzheimer’s disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology?

Overview of attention for article published in Translational Neurodegeneration, May 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
2 X users
facebook
1 Facebook page

Citations

dimensions_citation
26 Dimensions

Readers on

mendeley
102 Mendeley
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Title
Impact of the biological definition of Alzheimer’s disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology?
Published in
Translational Neurodegeneration, May 2018
DOI 10.1186/s40035-018-0117-9
Pubmed ID
Authors

S. Gauthier, H. Zhang, K. P. Ng, T.A. Pascoal, P. Rosa-Neto

Abstract

The NIA-AA research framework proposes a biological definition of Alzheimer's disease, where asymptomatic persons with amyloid deposition would be considered as having this disease prior to symptoms. Notwithstanding the fact that amyloid deposition in isolation is not associated with dementia, even the combined association of amyloid and tau pathology does not inevitably need to dementia over age 65. Other pathological factors may play a leading or an accelerating role in age-associated cognitive decline, including vascular small vessel disease, neuroinflammation and Lewy Body pathology. Research should aim at understanding the interaction between all these factors, rather than focusing on them individually. Hopefully this will lead to a personalized approach to the prevention of brain aging, based on individual biological, genetic and cognitive profiles.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 102 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 16%
Researcher 14 14%
Student > Ph. D. Student 12 12%
Other 7 7%
Student > Postgraduate 7 7%
Other 13 13%
Unknown 33 32%
Readers by discipline Count As %
Neuroscience 22 22%
Medicine and Dentistry 13 13%
Biochemistry, Genetics and Molecular Biology 7 7%
Psychology 5 5%
Nursing and Health Professions 3 3%
Other 12 12%
Unknown 40 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2018.
All research outputs
#2,257,193
of 25,382,440 outputs
Outputs from Translational Neurodegeneration
#77
of 384 outputs
Outputs of similar age
#46,063
of 344,075 outputs
Outputs of similar age from Translational Neurodegeneration
#1
of 5 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,075 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them