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Adherence to antiretroviral therapy and associated factors among HIV positive adults attending care and treatment in University of Gondar Referral Hospital, Northwest Ethiopia

Overview of attention for article published in BMC Infectious Diseases, June 2018
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Title
Adherence to antiretroviral therapy and associated factors among HIV positive adults attending care and treatment in University of Gondar Referral Hospital, Northwest Ethiopia
Published in
BMC Infectious Diseases, June 2018
DOI 10.1186/s12879-018-3176-8
Pubmed ID
Authors

Abiyot Abeje Molla, Abebaw Addis Gelagay, Habtamu Sewunet Mekonnen, Destaw Fetene Teshome

Abstract

Antiretroviral therapy has an impressive clinical effect on the human immunodeficiency virus although its effectiveness depends mainly on the adherence of patients to the therapy. Therefore, this study aimed to assess adherence status and associated factors of antiretroviral therapy among HIV infected adults on ART at the University of Gondar Referral Hospital, northwest Ethiopia. An institutional based cross-sectional study was conducted from May to June 2015. The systematic random sampling technique was used to select 440 study participants. Data collected using an intervieweradministered questionnaire was entered using EPI Info version 7 and analyzed using SPSS version 20. Both bivariate and multivariate logistic regression analyses were done. In the multivariate analysis, variables with P-value ≤ 0.05 were considered statistically significant between independent variables and the outcome variable (medication adherence). Adjusted odds ratio (AOR) with a 95% confidence interval was used to determine the strength and direction of the association. A total of 440 participants were included in the study. The mean age of participants was 36.09 (SD ± 8.09) years. The overall rate of adherence to ART was 88.2% (95% CI = 85.2, 91.1). Urban residence (AOR = 6.99, 95% CI: 2.30, 21.27), no co-morbidity (AOR = 0.13, 95% CI: 0.05, 0.33), knowledge about HIV and ART (AOR = 7.54, 95% CI: 2.69, 21.15), and disclosed HIV status to partners (AOR = 3.65 (1.06, 12.61) and CD4 count of ≥ 500mm3 (AOR = 3.91, 95% CI: 1.19, 12.81) were significantly associated with adherence. In this study, the rate of adherence to antiretroviral therapy was low compared to WHO standard.. Prevention of co-morbidities, improving knowledge through health education, providing strong drug adherence counseling with more emphasis on the rural community, and encouraging HIV positive individuals to disclose their HIV status are crucial for ART adherence.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 159 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 159 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 25 16%
Student > Bachelor 16 10%
Lecturer 12 8%
Student > Ph. D. Student 11 7%
Researcher 10 6%
Other 29 18%
Unknown 56 35%
Readers by discipline Count As %
Nursing and Health Professions 44 28%
Medicine and Dentistry 26 16%
Immunology and Microbiology 5 3%
Social Sciences 5 3%
Psychology 4 3%
Other 17 11%
Unknown 58 36%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2018.
All research outputs
#11,599,746
of 13,055,200 outputs
Outputs from BMC Infectious Diseases
#4,162
of 4,862 outputs
Outputs of similar age
#235,169
of 270,374 outputs
Outputs of similar age from BMC Infectious Diseases
#1
of 1 outputs
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