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Cytokine release syndrome

Overview of attention for article published in Journal for Immunotherapy of Cancer, June 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#25 of 2,632)
  • High Attention Score compared to outputs of the same age (98th percentile)

Mentioned by

news
27 news outlets
blogs
1 blog
twitter
45 tweeters
patent
9 patents
wikipedia
13 Wikipedia pages

Citations

dimensions_citation
746 Dimensions

Readers on

mendeley
1022 Mendeley
citeulike
1 CiteULike
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Title
Cytokine release syndrome
Published in
Journal for Immunotherapy of Cancer, June 2018
DOI 10.1186/s40425-018-0343-9
Pubmed ID
Authors

Alexander Shimabukuro-Vornhagen, Philipp Gödel, Marion Subklewe, Hans Joachim Stemmler, Hans Anton Schlößer, Max Schlaak, Matthias Kochanek, Boris Böll, Michael S. von Bergwelt-Baildon

Abstract

During the last decade the field of cancer immunotherapy has witnessed impressive progress. Highly effective immunotherapies such as immune checkpoint inhibition, and T-cell engaging therapies like bispecific T-cell engaging (BiTE) single-chain antibody constructs and chimeric antigen receptor (CAR) T cells have shown remarkable efficacy in clinical trials and some of these agents have already received regulatory approval. However, along with growing experience in the clinical application of these potent immunotherapeutic agents comes the increasing awareness of their inherent and potentially fatal adverse effects, most notably the cytokine release syndrome (CRS). This review provides a comprehensive overview of the mechanisms underlying CRS pathophysiology, risk factors, clinical presentation, differential diagnoses, and prognostic factors. In addition, based on the current evidence we give practical guidance to the management of the cytokine release syndrome.

Twitter Demographics

The data shown below were collected from the profiles of 45 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 1,022 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1022 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 138 14%
Student > Master 120 12%
Researcher 118 12%
Student > Ph. D. Student 98 10%
Other 77 8%
Other 167 16%
Unknown 304 30%
Readers by discipline Count As %
Medicine and Dentistry 255 25%
Biochemistry, Genetics and Molecular Biology 147 14%
Immunology and Microbiology 74 7%
Pharmacology, Toxicology and Pharmaceutical Science 49 5%
Agricultural and Biological Sciences 41 4%
Other 123 12%
Unknown 333 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 226. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2022.
All research outputs
#122,601
of 21,466,132 outputs
Outputs from Journal for Immunotherapy of Cancer
#25
of 2,632 outputs
Outputs of similar age
#3,212
of 298,813 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#1
of 1 outputs
Altmetric has tracked 21,466,132 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,632 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,813 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them