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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Antibacterial activity of ethanolic extract and compounds from fruits of Tectona grandis (Verbenaceae)
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, August 2015
|
| DOI | 10.1186/s12906-015-0790-5 |
| Pubmed ID | |
| Authors |
Gabin Thierry M. Bitchagno, Leonard Sama Fonkeng, Théodora K. Kopa, Michel F. Tala, Hippolyte Kamdem Wabo, Christopher B. Tume, Pierre Tane, Jules-Roger Kuiate |
| Abstract |
Well known as teak, Tectona grandis is widely used in African folk medicine for its pharmacological relevance. In Cameroon, this species is a reputed laxative in the Northern Region while in the Western Region, it is used in the treatment of skin diseases and diarrhoea. Separation and isolation of compounds were performed using different chromatographic methods while their structures were elucidated by spectroscopic techniques including MS and NMR, and by comparison of data with those reported in the literature. Isolated compounds as well as crude ethanol extract were tested for their antibacterial activities using broth micro-dilution method against four Gram negative bacteria strains Escherichia coli (ATCC 8739), Pseudomonas aeruginosa (PA 01), Klebsiella pneumonia (ATCC 11296) and Escherichia aerogenes (ATCC 13048). Three known compounds were isolated, including two quinones and one triterpene. They were identified as tectograndone (1), 6-methyl-1,4-dihydroxyanthraquinone (2), and 2β-hydroxyursolic acid (3) respectively. Crude ethanol extract showed good activity against the bacteria strains tested with MIC of 64-256 μg/mL. Among the isolated metabolites, 6-methyl-1,4-dihydroxyanthraquinone exhibited a strong activity against Escherichia aerogenes with MIC of 16 μg/mL, while tectograndone showed a moderate activity against Escherichia coli with MIC of 32 μg/mL. The antibacterial screening of the fruits of this plant as well as that of compounds 1 and 2 is reported herein for the first time. The research work presented here shows that Tectona grandis fruits possess compounds which could be developed in the treatment of bacterial diseases. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 2% |
| Unknown | 58 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 10% |
| Unspecified | 4 | 7% |
| Lecturer | 3 | 5% |
| Student > Doctoral Student | 3 | 5% |
| Lecturer > Senior Lecturer | 2 | 3% |
| Other | 11 | 19% |
| Unknown | 30 | 51% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 7 | 12% |
| Unspecified | 4 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Chemistry | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 33 | 56% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2015.
All research outputs
#17,768,879
of 22,821,814 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,347
of 3,630 outputs
Outputs of similar age
#177,583
of 264,036 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#60
of 93 outputs
Altmetric has tracked 22,821,814 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,630 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,036 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.