Title |
The VICI-trial: high frequency oscillation versus conventional mechanical ventilation in newborns with congenital diaphragmatic hernia: an international multicentre randomized controlled trial
|
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Published in |
BMC Pediatrics, November 2011
|
DOI | 10.1186/1471-2431-11-98 |
Pubmed ID | |
Authors |
Lieke van den Hout, Dick Tibboel, Sanne Vijfhuize, Harma te Beest, Wim Hop, Irwin Reiss, The CDH-EURO Consortium |
Abstract |
Congenital diaphragmatic hernia (CDH) is a severe congenital anomaly of the diaphragm resulting in pulmonary hypoplasia and pulmonary hypertension. It is associated with a high risk of mortality and pulmonary morbidity. Previous retrospective studies have reported high frequency oscillatory ventilation (HFO) to reduce pulmonary morbidity in infants with CDH, while others indicated HFO to be associated with worse outcome. We therefore aimed to develop a randomized controlled trial to compare initial ventilatory treatment with high-frequency oscillation and conventional ventilation in infants with CDH. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 1% |
South Africa | 1 | 1% |
Unknown | 85 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 9 | 10% |
Researcher | 9 | 10% |
Student > Master | 9 | 10% |
Student > Bachelor | 8 | 9% |
Student > Ph. D. Student | 8 | 9% |
Other | 23 | 26% |
Unknown | 21 | 24% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 41 | 47% |
Nursing and Health Professions | 8 | 9% |
Agricultural and Biological Sciences | 2 | 2% |
Social Sciences | 2 | 2% |
Sports and Recreations | 2 | 2% |
Other | 5 | 6% |
Unknown | 27 | 31% |