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Inhibition of highly pathogenic PRRSV replication in MARC-145 cells by artificial microRNAs

Overview of attention for article published in Virology Journal, November 2011
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Title
Inhibition of highly pathogenic PRRSV replication in MARC-145 cells by artificial microRNAs
Published in
Virology Journal, November 2011
DOI 10.1186/1743-422x-8-491
Pubmed ID
Authors

Shuqi Xiao, Qiwei Wang, Jintao Gao, Liangliang Wang, Zuyong He, Delin Mo, Xiaohong Liu, Yaosheng Chen

Abstract

Highly pathogenic porcine reproductive and respiratory syndrome (HP-PRRS) has caused large economic losses in swine industry in recent years. However, current antiviral strategy could not effectively prevent and control this disease. In this research, five artificial microRNAs (amiRNAs) respectively targeted towards ORF5 (amirGP5-243, -370) and ORF6 (amirM-82, -217,-263) were designed and incorporated into a miRNA-based vector that mimics the backbone of murine miR-155 and permits high expression of amiRNAs in a GFP fused form mediated by RNA Pol II promoter CMV.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Colombia 1 4%
Denmark 1 4%
Germany 1 4%
Unknown 19 83%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 35%
Researcher 6 26%
Student > Doctoral Student 2 9%
Professor 1 4%
Other 1 4%
Other 2 9%
Unknown 3 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 61%
Veterinary Science and Veterinary Medicine 2 9%
Medicine and Dentistry 2 9%
Biochemistry, Genetics and Molecular Biology 1 4%
Unknown 4 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2011.
All research outputs
#15,881,108
of 23,592,647 outputs
Outputs from Virology Journal
#1,999
of 3,124 outputs
Outputs of similar age
#98,169
of 143,418 outputs
Outputs of similar age from Virology Journal
#51
of 91 outputs
Altmetric has tracked 23,592,647 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,124 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.8. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 143,418 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 91 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.