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Mendeley readers
Attention Score in Context
| Title |
In Vivo anti-trypanosomal activity of dichloromethane and methanol crude leaf extracts of Dovyalis abyssinica (Salicaceae) against Trypanosoma congolense
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, August 2015
|
| DOI | 10.1186/s12906-015-0809-y |
| Pubmed ID | |
| Authors |
Belay Tadesse, Getachew Terefe, Nigatu Kebede, Workineh Shibeshi |
| Abstract |
African trypanosomiasis affects both humans and livestock in sub-Saharan countries including Ethiopia. Due to limitations to current chemotherapy, there is an urgent need for the development of new, safe, cheap and effective drugs. In the present study, the leaf of Dovyalis abyssinica was tested for its in vivo antitrypanosomal activity against Trypanosoma congolense field isolate on mice. The leaf of D. abyssinica was macerated using dichloromethane and methanol. The extracts at doses of 250, 200, 150 and 100 mg/kg body weight were administered intraperitonealy daily for 7 days to mice infected with T. congolense. Following administration, parasitemia, packed cell volume, rectal temperature, body weight and survival time were monitored. Administration of dichloromethane and methanol extracts at 250 and 200 mg/kg reduced (p < 0.05) parasitemia and rectal temperature, and improved (p < 0.05) PCV, mean body weight, and mean survival time compared to dimethylsulfoxide treatment. Crude dichloromethane and methanol leaf extracts of D. abyssinica displayed anti-trypanosomal activity that may serve as lead for the development of effective alternative antitrypanosomal drugs. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 40 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 18% |
| Student > Master | 5 | 13% |
| Other | 3 | 8% |
| Student > Bachelor | 3 | 8% |
| Lecturer | 2 | 5% |
| Other | 5 | 13% |
| Unknown | 15 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 4 | 10% |
| Engineering | 3 | 8% |
| Agricultural and Biological Sciences | 3 | 8% |
| Veterinary Science and Veterinary Medicine | 2 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
| Other | 9 | 23% |
| Unknown | 17 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2021.
All research outputs
#18,423,683
of 22,824,164 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,510
of 3,631 outputs
Outputs of similar age
#190,614
of 264,379 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#63
of 93 outputs
Altmetric has tracked 22,824,164 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,631 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,379 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.