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Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

Overview of attention for article published in BMC Cancer, January 2008
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Mentioned by

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Citations

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248 Dimensions

Readers on

mendeley
151 Mendeley
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2 CiteULike
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Title
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
Published in
BMC Cancer, January 2008
DOI 10.1186/1471-2407-8-17
Pubmed ID
Authors

Joshua Z Press, Alessandro De Luca, Niki Boyd, Sean Young, Armelle Troussard, Yolanda Ridge, Pardeep Kaurah, Steve E Kalloger, Katherine A Blood, Margaret Smith, Paul T Spellman, Yuker Wang, Dianne M Miller, Doug Horsman, Malek Faham, C Blake Gilks, Joe Gray, David G Huntsman

Abstract

Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis. Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as promoter hypermethylation can lead to decreased expression of BRCA1/2 in ovarian cancers. The mechanism of BRCA1/2 loss is a potential method of subclassifying high grade serous carcinomas.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 2 1%
Netherlands 1 <1%
United Kingdom 1 <1%
Unknown 147 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 33 22%
Researcher 30 20%
Student > Master 18 12%
Other 10 7%
Student > Doctoral Student 7 5%
Other 28 19%
Unknown 25 17%
Readers by discipline Count As %
Medicine and Dentistry 50 33%
Agricultural and Biological Sciences 33 22%
Biochemistry, Genetics and Molecular Biology 21 14%
Unspecified 4 3%
Chemistry 3 2%
Other 11 7%
Unknown 29 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2011.
All research outputs
#15,238,442
of 22,656,971 outputs
Outputs from BMC Cancer
#4,098
of 8,237 outputs
Outputs of similar age
#129,931
of 155,022 outputs
Outputs of similar age from BMC Cancer
#7
of 10 outputs
Altmetric has tracked 22,656,971 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,237 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 155,022 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.