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sRAGE in diabetic and non-diabetic critically ill patients: effects of intensive insulin therapy

Overview of attention for article published in Critical Care, August 2011
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Title
sRAGE in diabetic and non-diabetic critically ill patients: effects of intensive insulin therapy
Published in
Critical Care, August 2011
DOI 10.1186/cc10420
Pubmed ID
Authors

Yaseen M Arabi, Mohammed Dehbi, Asgar H Rishu, Engin Baturcam, Salim H Kahoul, Riette J Brits, Brintha Naidu, Abderrezak Bouchama

Abstract

Hyperglycemia represents an independent prognostic factor in critically ill non-diabetic patients but not in those with diabetes. In this context, there is an ongoing debate on the benefit of an intensive insulin therapy, particularly in diabetic patients. We tested the hypothesis that expression of the receptor for advanced glycation end-products (RAGE), an important signal transduction receptor that elicits long-lasting nuclear factor kappa B (NF-κB) activation, may underlie this difference. RAGE expression is regulated by multiple ligands, including high mobility group box-1 (HMGB-1), and is reflected by its released soluble form (sRAGE).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 2%
France 1 2%
Saudi Arabia 1 2%
Brazil 1 2%
Unknown 56 93%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 18%
Other 8 13%
Researcher 8 13%
Student > Ph. D. Student 5 8%
Student > Postgraduate 4 7%
Other 9 15%
Unknown 15 25%
Readers by discipline Count As %
Medicine and Dentistry 26 43%
Nursing and Health Professions 4 7%
Biochemistry, Genetics and Molecular Biology 3 5%
Social Sciences 3 5%
Agricultural and Biological Sciences 2 3%
Other 5 8%
Unknown 17 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2011.
All research outputs
#17,285,668
of 25,374,647 outputs
Outputs from Critical Care
#5,469
of 6,554 outputs
Outputs of similar age
#95,729
of 134,836 outputs
Outputs of similar age from Critical Care
#40
of 57 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 134,836 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.