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A systematic review and meta-analysis of vertical transmission route of HIV in Ethiopia

Overview of attention for article published in BMC Infectious Diseases, June 2018
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Title
A systematic review and meta-analysis of vertical transmission route of HIV in Ethiopia
Published in
BMC Infectious Diseases, June 2018
DOI 10.1186/s12879-018-3189-3
Pubmed ID
Authors

Aklilu Endalamaw, Amare Demsie, Setegn Eshetie, Tesfa Dejenie Habtewold

Abstract

The burden of mother-to-child transmission rate of HIV is high and risk factors are common in Ethiopia. This systematic review and meta-analysis intended to provide the pooled estimation of mother-to-child transmission rate and its risk factors in Ethiopia. We searched PubMed, Google Scholar, EMBASE and Web of Science electronic databases for all available references. We included observational studies including case-control, cohort, and cross-sectional studies. The search was further limited to studies conducted in Ethiopia and publish in English. Heterogeneity was checked using the I2 statistic. Egger's test and the funnel plot were used to assess publication bias. A meta-analysis using a weighted inverse variance random-effects model was performed. A total of 18 studies with 6253 individuals were included in this systematic review and meta-analysis. Of these, 14 studies with 4624 individuals were used to estimate the prevalence. The estimated pooled prevalence of mother-to-child transmission of HIV was 11.4% (95% CI = 9.1-13.7). The pooled adjusted odds ratio (AOR) of mother-to-child transmission of HIV for the infants from rural area was 3.8 (95% CI = 1.4 to 6.3), infants delivered at home was 3.2 (95% CI = 1.2 to 5.2), infant didn't take antiretroviral prophylaxis was 5.8 (95% CI = 1.5 to 10.3), mother didn't take antiretroviral prophylaxis was 6.1 (95% CI = 2.5 to 9.6), mothers didn't receive PMTCT intervention was 5.1 (95% CI = 1.6, 8.6), and on mixed feeding was 4.3 (95% CI = 1.8 to 6.7). This systematic review and meta-analysis showed that mother-to-child transmission rate of HIV was high in Ethiopia. Being from the rural residence, home delivery, not taking antiretroviral prophylaxis, the absence of PMTCT intervention, and mixed infant feeding practices increased the risk of HIV transmission. It is registered in the Prospero database: (PROSPERO 2017: CRD42017078232 ).

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 167 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 167 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 10%
Researcher 15 9%
Student > Ph. D. Student 12 7%
Student > Doctoral Student 10 6%
Student > Bachelor 10 6%
Other 27 16%
Unknown 77 46%
Readers by discipline Count As %
Medicine and Dentistry 34 20%
Nursing and Health Professions 23 14%
Biochemistry, Genetics and Molecular Biology 5 3%
Agricultural and Biological Sciences 4 2%
Immunology and Microbiology 4 2%
Other 17 10%
Unknown 80 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 September 2018.
All research outputs
#14,276,692
of 23,323,574 outputs
Outputs from BMC Infectious Diseases
#3,662
of 7,805 outputs
Outputs of similar age
#180,129
of 329,371 outputs
Outputs of similar age from BMC Infectious Diseases
#63
of 148 outputs
Altmetric has tracked 23,323,574 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,805 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,371 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 148 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.