Title |
Emerging trends and persistent challenges in the management of adult syphilis
|
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Published in |
BMC Infectious Diseases, August 2015
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DOI | 10.1186/s12879-015-1028-3 |
Pubmed ID | |
Authors |
Susan Tuddenham, Khalil G. Ghanem |
Abstract |
There are an estimated 10.6 million incident cases of syphilis worldwide each year. We highlight some persistent challenges and emerging trends in the clinical management of syphilis with a particular focus on therapy, serology, diagnostics, and prevention. Decades after the introduction of penicillin, the optimal management of early syphilis continues to be a controversial topic, particularly in the setting of HIV co-infection. Similarly, the need for routine lumbar puncture in HIV co-infected asymptomatic persons is an unanswered question. Despite advances in both automation and point-of-care diagnostics, we continue to rely on indirect measures of disease activity to manage this infection. As syphilis rates in some populations continue to rise, novel and effective prevention strategies are needed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 22% |
United Kingdom | 1 | 11% |
Brazil | 1 | 11% |
United Arab Emirates | 1 | 11% |
Unknown | 4 | 44% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 78% |
Practitioners (doctors, other healthcare professionals) | 2 | 22% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 2 | 2% |
Spain | 1 | 1% |
Unknown | 91 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 18 | 19% |
Researcher | 12 | 13% |
Student > Master | 10 | 11% |
Other | 8 | 9% |
Student > Postgraduate | 8 | 9% |
Other | 21 | 22% |
Unknown | 17 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 43% |
Agricultural and Biological Sciences | 9 | 10% |
Nursing and Health Professions | 6 | 6% |
Immunology and Microbiology | 4 | 4% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Other | 14 | 15% |
Unknown | 17 | 18% |