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Synaptopathy, circuitopathy and the computational biology of Huntington’s disease

Overview of attention for article published in BMC Biology, June 2018
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Title
Synaptopathy, circuitopathy and the computational biology of Huntington’s disease
Published in
BMC Biology, June 2018
DOI 10.1186/s12915-018-0539-y
Pubmed ID
Authors

Anthony J. Hannan

Abstract

Huntington's disease (HD) is one of the most common tandem repeat disorders and presents as a unique trilogy of cognitive, psychiatric and motor symptoms. One of the major mysteries of HD is why it selectively affects specific neuronal populations. A new article in BMC Biology provides a piece in the puzzle of pathogenesis. By demonstrating the delicate relationship between cortical and striatal neurons, it provokes broader questions of how we might understand HD as a disorder of synapses, neural circuits and systems biology.

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The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 13%
Researcher 3 13%
Student > Ph. D. Student 3 13%
Student > Bachelor 2 9%
Student > Doctoral Student 1 4%
Other 1 4%
Unknown 10 43%
Readers by discipline Count As %
Medicine and Dentistry 4 17%
Neuroscience 3 13%
Biochemistry, Genetics and Molecular Biology 2 9%
Nursing and Health Professions 2 9%
Psychology 1 4%
Other 2 9%
Unknown 9 39%