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Parkinson's disease‐associated protein Parkin: an unusual player in cancer

Overview of attention for article published in Cancer Communications, June 2018
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Title
Parkinson's disease‐associated protein Parkin: an unusual player in cancer
Published in
Cancer Communications, June 2018
DOI 10.1186/s40880-018-0314-z
Pubmed ID
Authors

Juan Liu, Cen Zhang, Wenwei Hu, Zhaohui Feng

Abstract

The mutation of the Parkin gene is a cause of familial Parkinson's disease. A growing body of evidence suggests that Parkin also functions as a tumor suppressor. Parkin is an ubiquitin E3 ligase, and plays important roles in a variety of cellular processes implicated in tumorigenesis, including cell cycle, cell proliferation, apoptosis, metastasis, mitophagy and metabolic reprogramming. Here we review the role and mechanism of Parkin in cancer.

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Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 62 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 15%
Student > Bachelor 9 15%
Student > Ph. D. Student 7 11%
Student > Master 5 8%
Student > Postgraduate 3 5%
Other 6 10%
Unknown 23 37%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 24%
Medicine and Dentistry 8 13%
Neuroscience 6 10%
Agricultural and Biological Sciences 5 8%
Nursing and Health Professions 1 2%
Other 4 6%
Unknown 23 37%