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Oral Candida albicans isolates from HIV-positive individuals have similar in vitro biofilm-forming ability and pathogenicity as invasive Candida isolates

Overview of attention for article published in BMC Microbiology, November 2011
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Title
Oral Candida albicans isolates from HIV-positive individuals have similar in vitro biofilm-forming ability and pathogenicity as invasive Candida isolates
Published in
BMC Microbiology, November 2011
DOI 10.1186/1471-2180-11-247
Pubmed ID
Authors

Juliana C Junqueira, Beth B Fuchs, Maged Muhammed, Jeffrey J Coleman, Jamal MAH Suleiman, Simone FG Vilela, Anna CBP Costa, Vanessa MC Rasteiro, Antonio OC Jorge, Eleftherios Mylonakis

Abstract

Candida can cause mucocutaneous and/or systemic infections in hospitalized and immunosuppressed patients. Most individuals are colonized by Candida spp. as part of the oral flora and the intestinal tract. We compared oral and systemic isolates for the capacity to form biofilm in an in vitro biofilm model and pathogenicity in the Galleria mellonella infection model. The oral Candida strains were isolated from the HIV patients and included species of C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, C. krusei, C. norvegensis, and C. dubliniensis. The systemic strains were isolated from patients with invasive candidiasis and included species of C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, C. lusitaniae, and C. kefyr. For each of the acquired strains, biofilm formation was evaluated on standardized samples of silicone pads and acrylic resin. We assessed the pathogenicity of the strains by infecting G. mellonella animals with Candida strains and observing survival.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 1%
Denmark 1 1%
Unknown 86 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 14%
Student > Ph. D. Student 10 11%
Student > Bachelor 9 10%
Researcher 8 9%
Professor 7 8%
Other 21 24%
Unknown 21 24%
Readers by discipline Count As %
Medicine and Dentistry 26 30%
Agricultural and Biological Sciences 17 19%
Biochemistry, Genetics and Molecular Biology 8 9%
Immunology and Microbiology 8 9%
Business, Management and Accounting 1 1%
Other 5 6%
Unknown 23 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2011.
All research outputs
#17,286,379
of 25,374,647 outputs
Outputs from BMC Microbiology
#1,937
of 3,489 outputs
Outputs of similar age
#106,222
of 153,528 outputs
Outputs of similar age from BMC Microbiology
#15
of 25 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,489 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 153,528 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.