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Mendeley readers
Attention Score in Context
| Title |
Fish oil administration mediates apoptosis of Walker 256 tumor cells by modulation of p53, Bcl-2, caspase-7 and caspase-3 protein expression
|
|---|---|
| Published in |
Lipids in Health and Disease, August 2015
|
| DOI | 10.1186/s12944-015-0098-y |
| Pubmed ID | |
| Authors |
Gina Borghetti, Adriana Aya Yamaguchi, Julia Aikawa, Ricardo Key Yamazaki, Gleisson Alisson Pereira de Brito, Luiz Claudio Fernandes |
| Abstract |
Several studies have been shown pro-apoptotic effects of fish oil (FO), rich in n-3 polyunsaturated fatty acids (n-3 PUFA) on cancer cells. Nevertheless, few in vivo experiments have provided data of its ability on apoptosis protein expression in tumor tissue. Thus, in this study we investigate the effect of FO supplementation on apoptosis protein expression in Walker 256 tumor bearing rats. Male Wistar rats were randomly assigned to three groups: fed with regular chow (W); fed regular chow supplemented with FO (WFO) or coconut fat (WCO) (1 g/kg body weight/daily). After thirty days, all animals were inoculated subcutaneously with Walker 256 tumor cells. Protein expression was done by western blotting in Walker 256 tumor tissue samples. FO decreased the Bcl-2/Bax ratio (p < 0.05) and increased the p53 (p < 0.05), cleaved caspase-7 (p < 0.05) and cleaved caspase-3 (p < 0.05) in Walker 256 tumor tissue. Our data suggest that the pro-apoptotic effect of FO in Walker 256 tumor is related with specifics cleaved caspases. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 24% |
| Lecturer | 2 | 12% |
| Lecturer > Senior Lecturer | 1 | 6% |
| Student > Bachelor | 1 | 6% |
| Professor | 1 | 6% |
| Other | 5 | 29% |
| Unknown | 3 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 4 | 24% |
| Nursing and Health Professions | 3 | 18% |
| Medicine and Dentistry | 3 | 18% |
| Biochemistry, Genetics and Molecular Biology | 2 | 12% |
| Sports and Recreations | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 4 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2016.
All research outputs
#18,146,485
of 23,312,088 outputs
Outputs from Lipids in Health and Disease
#943
of 1,475 outputs
Outputs of similar age
#182,054
of 268,581 outputs
Outputs of similar age from Lipids in Health and Disease
#23
of 38 outputs
Altmetric has tracked 23,312,088 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,475 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,581 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.