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Genome sequencing of herb Tulsi (Ocimum tenuiflorum) unravels key genes behind its strong medicinal properties

Overview of attention for article published in BMC Plant Biology, August 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#16 of 2,991)
  • High Attention Score compared to outputs of the same age (96th percentile)

Mentioned by

5 news outlets
11 tweeters
3 Wikipedia pages
1 Google+ user


67 Dimensions

Readers on

139 Mendeley
1 CiteULike
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Genome sequencing of herb Tulsi (Ocimum tenuiflorum) unravels key genes behind its strong medicinal properties
Published in
BMC Plant Biology, August 2015
DOI 10.1186/s12870-015-0562-x
Pubmed ID

Atul K. Upadhyay, Anita R. Chacko, A. Gandhimathi, Pritha Ghosh, K. Harini, Agnel P. Joseph, Adwait G. Joshi, Snehal D. Karpe, Swati Kaushik, Nagesh Kuravadi, Chandana S Lingu, J. Mahita, Ramya Malarini, Sony Malhotra, Manoharan Malini, Oommen K. Mathew, Eshita Mutt, Mahantesha Naika, Sathyanarayanan Nitish, Shaik Naseer Pasha, Upadhyayula S. Raghavender, Anantharamanan Rajamani, S Shilpa, Prashant N. Shingate, Heikham Russiachand Singh, Anshul Sukhwal, Margaret S. Sunitha, Manojkumar Sumathi, S. Ramaswamy, Malali Gowda, Ramanathan Sowdhamini


Krishna Tulsi, a member of Lamiaceae family, is a herb well known for its spiritual, religious and medicinal importance in India. The common name of this plant is 'Tulsi' (or 'Tulasi' or 'Thulasi') and is considered sacred by Hindus. We present the draft genome of Ocimum tenuiflurum L (subtype Krishna Tulsi) in this report. The paired-end and mate-pair sequence libraries were generated for the whole genome sequenced with the Illumina Hiseq 1000, resulting in an assembled genome of 374 Mb, with a genome coverage of 61 % (612 Mb estimated genome size). We have also studied transcriptomes (RNA-Seq) of two subtypes of O. tenuiflorum, Krishna and Rama Tulsi and report the relative expression of genes in both the varieties. The pathways leading to the production of medicinally-important specialized metabolites have been studied in detail, in relation to similar pathways in Arabidopsis thaliana and other plants. Expression levels of anthocyanin biosynthesis-related genes in leaf samples of Krishna Tulsi were observed to be relatively high, explaining the purple colouration of Krishna Tulsi leaves. The expression of six important genes identified from genome data were validated by performing q-RT-PCR in different tissues of five different species, which shows the high extent of urosolic acid-producing genes in young leaves of the Rama subtype. In addition, the presence of eugenol and ursolic acid, implied as potential drugs in the cure of many diseases including cancer was confirmed using mass spectrometry. The availability of the whole genome of O.tenuiflorum and our sequence analysis suggests that small amino acid changes at the functional sites of genes involved in metabolite synthesis pathways confer special medicinal properties to this herb.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 2 1%
United States 1 <1%
Unknown 136 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 24%
Researcher 22 16%
Student > Master 13 9%
Student > Bachelor 8 6%
Other 7 5%
Other 20 14%
Unknown 35 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 52 37%
Biochemistry, Genetics and Molecular Biology 21 15%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Medicine and Dentistry 4 3%
Chemistry 3 2%
Other 14 10%
Unknown 40 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 54. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2022.
All research outputs
of 21,252,842 outputs
Outputs from BMC Plant Biology
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Outputs of similar age
of 253,197 outputs
Outputs of similar age from BMC Plant Biology
of 1 outputs
Altmetric has tracked 21,252,842 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,991 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,197 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them