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Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming

Overview of attention for article published in Stem Cell Research & Therapy, September 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

blogs
2 blogs
twitter
9 X users
patent
2 patents

Citations

dimensions_citation
161 Dimensions

Readers on

mendeley
218 Mendeley
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Title
Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming
Published in
Stem Cell Research & Therapy, September 2015
DOI 10.1186/s13287-015-0150-x
Pubmed ID
Authors

Peter J. Quesenberry, Jason Aliotta, Maria Chiara Deregibus, Giovanni Camussi

Abstract

Growing evidence suggests that transcriptional regulators and secreted RNA molecules encapsulated within membrane vesicles modify the phenotype of target cells. Membrane vesicles, actively released by cells, represent a mechanism of intercellular communication that is conserved evolutionarily and involves the transfer of molecules able to induce epigenetic changes in recipient cells. Extracellular vesicles, which include exosomes and microvesicles, carry proteins, bioactive lipids, and nucleic acids, which are protected from enzyme degradation. These vesicles can transfer signals capable of altering cell function and/or reprogramming targeted cells. In the present review we focus on the extracellular vesicle-induced epigenetic changes in recipient cells that may lead to phenotypic and functional modifications. The relevance of these phenomena in stem cell biology and tissue repair is discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 218 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Germany 2 <1%
Denmark 2 <1%
United Kingdom 1 <1%
Mexico 1 <1%
Unknown 209 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 59 27%
Student > Master 29 13%
Researcher 28 13%
Student > Bachelor 24 11%
Student > Doctoral Student 13 6%
Other 28 13%
Unknown 37 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 58 27%
Agricultural and Biological Sciences 45 21%
Medicine and Dentistry 33 15%
Engineering 11 5%
Neuroscience 5 2%
Other 17 8%
Unknown 49 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2022.
All research outputs
#1,640,528
of 23,838,611 outputs
Outputs from Stem Cell Research & Therapy
#80
of 2,530 outputs
Outputs of similar age
#22,777
of 269,101 outputs
Outputs of similar age from Stem Cell Research & Therapy
#1
of 55 outputs
Altmetric has tracked 23,838,611 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,530 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,101 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.