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Factors associated with red blood cell transfusions in very-low-birth-weight preterm infants in Brazilian neonatal units

Overview of attention for article published in BMC Pediatrics, September 2015
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Title
Factors associated with red blood cell transfusions in very-low-birth-weight preterm infants in Brazilian neonatal units
Published in
BMC Pediatrics, September 2015
DOI 10.1186/s12887-015-0432-6
Pubmed ID
Authors

Amelia Miyashiro Nunes dos Santos, Ruth Guinsburg, Maria Fernanda Branco de Almeida, Renato Soibelman Procianoy, Sergio Tadeu Martins Marba, Walusa Assad Gonçalves Ferri, Ligia MariaSuppo de Souza Rugolo, José Maria Andrade Lopes, Maria Elisabeth Lopes Moreira, Jorge Hecker Luz, Maria Rafaela Conde González, Jucille do Amaral Meneses, Regina Vieira Cavalcante da Silva, Vânia Olivetti Steffen Abdallah, José Luiz Muniz Bandeira Duarte, Patricia Franco Marques, Maria Albertina Santiago Rego, Navantino Alves Filho, Vera Lúcia Jornada Krebs, For the Brazilian Network on Neonatal Research

Abstract

Preterm infants in neonatal intensive care units frequently receive red blood cells (RBC) transfusions due to the anemia of prematurity. A number of variables related to gestational age, severity of illness and transfusion practices adopted in the neonatal unit where the neonate was born may contribute to the prescription of RBC transfusions. This study aimed to analyse the frequency and factors associated with RBC transfusions in very-low-birth-weight preterm infants. A prospective cohort of 4283 preterm infants (gestational age: 29.9 ± 2.9 weeks; birth weight: 1084 ± 275 g) carried out at 16 university hospitals in Brazil between January 2009 and December 2011 was analysed. Factors associated with RBC transfusions were evaluated using univariate and multiple logistic regression analysis. A total of 2208 (51.6 %) infants received RBC transfusions (variation per neonatal unit: 34.1 % to 66.4 %). RBC transfusions were significantly associated with gestational age (OR: -1.098; 95%CI: -1.12 to -1.04), SNAPPE II score (1.01; 1.00-1.02), apnea (1.69; 1.34-2.14), pulmonary hemorrhage (2.65; 1.74-4.031), need for oxygen at 28 days of life (1.56; 1.17-2.08), clinical sepsis (3.22; 2.55-4.05), necrotising enterocolitis (3.80; 2.26-6.41), grades III/IV intraventricular hemorrhage (1.64; 1.05-2.58), mechanical ventilation (2.27; 1.74-2.97), use of umbilical catheter (1.86; 1.35-2.57), parenteral nutrition (2.06; 1.27-3.33), >60 days of hospitalization (5.29; 4.02-6.95) and the neonatal unit where the neonate was born. The frequency of RBC transfusions varied among neonatal intensive care units. Even after adjusting for adverse health conditions and therapeutic interventions, the neonatal unit continued to influence transfusion practices in very-low birth-weight infants.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Canada 1 <1%
Unknown 105 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 12%
Student > Postgraduate 11 10%
Student > Doctoral Student 10 9%
Student > Ph. D. Student 8 7%
Researcher 6 6%
Other 24 22%
Unknown 35 33%
Readers by discipline Count As %
Medicine and Dentistry 45 42%
Nursing and Health Professions 8 7%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Unspecified 2 2%
Biochemistry, Genetics and Molecular Biology 2 2%
Other 7 7%
Unknown 39 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2015.
All research outputs
#14,824,070
of 22,826,360 outputs
Outputs from BMC Pediatrics
#1,908
of 3,006 outputs
Outputs of similar age
#147,462
of 267,016 outputs
Outputs of similar age from BMC Pediatrics
#35
of 62 outputs
Altmetric has tracked 22,826,360 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,006 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,016 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.