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Mendeley readers
Attention Score in Context
| Title |
Serum microRNA profiling to distinguish papillary thyroid cancer from benign thyroid masses
|
|---|---|
| Published in |
Journal of Otolaryngology - Head & Neck Surgery, September 2015
|
| DOI | 10.1186/s40463-015-0083-5 |
| Pubmed ID | |
| Authors |
M. Elise R. Graham, Robert D. Hart, Susan Douglas, Fawaz M. Makki, Devanand Pinto, Angela L. Butler, Martin Bullock, Matthew H. Rigby, Jonathan R. B. Trites, S. Mark Taylor, Rama Singh |
| Abstract |
Papillary thyroid cancer (PTC) is increasing in incidence. Fine needle aspiration is the gold standard for diagnosis, but results can be indeterminate. Identifying tissue and serum biomarkers, like microRNA, is therefore desirable. We sought to identify miRNA that is differentially expressed in the serum of patients with PTC. Serum miRNA was quantified in 31 female thyroidectomy patients: 13 with benign disease and 18 with PTC. qPCR results were compared for significant fold-changes in 175 miRNAs, against a pooled control. 128 miRNA qualified for analysis. There were identifiable fold-changes in miRNA levels between benign and control, and between PTC and control. There were statistically significant fold changes in the level of four miRNAs between benign and PTC: hsa-miR-146a-5p and hsa-miR-199b-3p were down-regulated, while hsa-let7b-5p and hsa-miR-10a-5p were up-regulated. MicroRNA is differentially expressed in the serum of patients with PTC. Serum miRNA has the potential to aid in thyroid cancer diagnosis. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 21% |
| Student > Ph. D. Student | 9 | 17% |
| Student > Master | 7 | 13% |
| Student > Bachelor | 4 | 8% |
| Professor | 3 | 6% |
| Other | 11 | 21% |
| Unknown | 8 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 28% |
| Biochemistry, Genetics and Molecular Biology | 11 | 21% |
| Agricultural and Biological Sciences | 10 | 19% |
| Unspecified | 2 | 4% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Other | 3 | 6% |
| Unknown | 11 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2015.
All research outputs
#15,799,182
of 25,457,858 outputs
Outputs from Journal of Otolaryngology - Head & Neck Surgery
#255
of 629 outputs
Outputs of similar age
#143,015
of 278,187 outputs
Outputs of similar age from Journal of Otolaryngology - Head & Neck Surgery
#2
of 11 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 629 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,187 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.