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Distribution of resistance genes encoding ESBLs in Enterobacteriaceae isolated from biological samples in health centers in Ouagadougou, Burkina Faso

Overview of attention for article published in BMC Research Notes, July 2018
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Title
Distribution of resistance genes encoding ESBLs in Enterobacteriaceae isolated from biological samples in health centers in Ouagadougou, Burkina Faso
Published in
BMC Research Notes, July 2018
DOI 10.1186/s13104-018-3581-5
Pubmed ID
Authors

Dissinviel S. Kpoda, Abraham Ajayi, Marius Somda, Oumar Traore, Nathalie Guessennd, Aboubakar S. Ouattara, Lassana Sangare, Alfred S. Traore, Mireille Dosso

Abstract

Resistance to antibiotics most especially third generation cephalosporins has assumed a worrisome dimension globally. Genes conferring these resistance which are mediated by enzymes known as extended spectrum beta-lactamases (ESBLs) are now wide spread among several Enterobacteriaceae species. However there is paucity of data regarding the distribution of these genes in Burkina Faso. Hence this prospective study aims to determine the prevalence and distribution of ESBL encoding genes in ESBL producing Enterobacteriaceae strains isolated from clinical samples of patients attending the three major hospitals in Ouagadougou Burkina Faso. ESBL-encoding genes were assayed in 187 ESBL producing Enterobacteriaceae strains. Among these isolates, the prevalence of ESBL-producing strains with blaTEM, blaSHV and blaCTX-M genes were 26.2% (49/187), 5.9% (11/187) and 40.1% (75/187) respectively. The association of ESBL encoding genes with health centers was statistically significant (p = 0.0209). Approximately 39.6% of E. coli harbored CTX-M and Klebsiella spp. 5.9%. This study demonstrates the dissemination of TEM, SHV and CTX-M genes in ESBL producing Enterobacteriaceae strains in Ouagadougou. Continuous spread of these bacteria poses great public health risk, thus increased surveillance and regulation of antibiotics use is imperative in Burkina Faso.

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The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 84 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 12%
Student > Bachelor 9 11%
Student > Postgraduate 6 7%
Student > Doctoral Student 5 6%
Other 4 5%
Other 14 17%
Unknown 36 43%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 13%
Immunology and Microbiology 10 12%
Medicine and Dentistry 7 8%
Agricultural and Biological Sciences 5 6%
Nursing and Health Professions 5 6%
Other 10 12%
Unknown 36 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2018.
All research outputs
#20,527,576
of 23,096,849 outputs
Outputs from BMC Research Notes
#3,583
of 4,287 outputs
Outputs of similar age
#286,411
of 327,048 outputs
Outputs of similar age from BMC Research Notes
#113
of 142 outputs
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We're also able to compare this research output to 142 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.