Title |
Identification of Schizosaccharomyces pombe in the guts of healthy individuals and patients with colorectal cancer: preliminary evidence from a gut microbiome secretome study
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Published in |
Gut Pathogens, July 2018
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DOI | 10.1186/s13099-018-0258-5 |
Pubmed ID | |
Authors |
Siok-Fong Chin, Putri Intan Hafizah Megat Mohd Azlan, Luqman Mazlan, Hui-min Neoh |
Abstract |
Over the years, genetic profiling of the gut microbiome of patients with colorectal cancer (CRC) using genome sequencing has suggested over-representation of several bacterial taxa. However, little is known about the protein or metabolite secretions from the microbiota that could lead to CRC pathology. Proteomic studies on the role of microbial secretome in CRC are relatively rare. Here, we report the identification of proteins from Schizosaccharomyces pombe found in the stool samples of both healthy individuals and patients with CRC. We found that distinctive sets of S. pombe proteins were present exclusively and in high intensities in each group. Our finding may trigger a new interest in the role of gut mycobiota in carcinogenesis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 21% |
Researcher | 4 | 14% |
Student > Ph. D. Student | 3 | 10% |
Lecturer | 2 | 7% |
Other | 1 | 3% |
Other | 4 | 14% |
Unknown | 9 | 31% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 8 | 28% |
Chemistry | 4 | 14% |
Agricultural and Biological Sciences | 2 | 7% |
Medicine and Dentistry | 2 | 7% |
Unspecified | 1 | 3% |
Other | 1 | 3% |
Unknown | 11 | 38% |