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Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, July 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Mentioned by

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1 news outlet
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4 X users

Citations

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23 Dimensions

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14 Mendeley
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Title
Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria
Published in
Allergy, Asthma & Clinical Immunology, July 2018
DOI 10.1186/s13223-018-0255-8
Pubmed ID
Authors

R. Grzanka, A. Damasiewicz-Bodzek, A. Kasperska-Zajac

Abstract

Chronic spontaneous urticaria (CSU) is associated with activation of systemic inflammatory response and coagulation/fibrinolysis. To study whether there is a relationship between the acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria (CSU) patients. Serum concentrations of C-reactive protein (CRP) and interleukin 6 (IL-6), key markers of acute phase response and of D-dimer, a marker of fibrin turnover were investigated in 58 CSU patients assessed with the urticaria activity score (UAS) and the controls. Serum concentrations of IL-6, CRP, and D-dimer were significantly higher in CSU patients as compared with the controls. We found statistically significant correlations between D-dimers concentrations and the inflammatory markers: CRP and IL-6 as well as UAS. Markers of inflammation (IL-6 and CRP) and of fibrinolysis (D-dimer) are related to each other in CSU, suggesting a possible cross-talk between inflammation and coagulation/fibrinolysis. It might be implicated in pathogenesis of the disease and may be associated with higher risks of cardiovascular diseases in CSU patients.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 21%
Student > Postgraduate 3 21%
Student > Doctoral Student 3 21%
Other 1 7%
Researcher 1 7%
Other 1 7%
Unknown 2 14%
Readers by discipline Count As %
Medicine and Dentistry 7 50%
Biochemistry, Genetics and Molecular Biology 2 14%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Social Sciences 1 7%
Computer Science 1 7%
Other 0 0%
Unknown 2 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2018.
All research outputs
#2,761,240
of 25,382,440 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#158
of 924 outputs
Outputs of similar age
#54,060
of 340,475 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#4
of 13 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,475 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.