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Falciparum malaria molecular drug resistance in the Democratic Republic of Congo: a systematic review

Overview of attention for article published in Malaria Journal, September 2015
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  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

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88 Mendeley
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Title
Falciparum malaria molecular drug resistance in the Democratic Republic of Congo: a systematic review
Published in
Malaria Journal, September 2015
DOI 10.1186/s12936-015-0892-z
Pubmed ID
Authors

Dieudonné Makaba Mvumbi, Jean-Marie Kayembe, Hippolyte Situakibanza, Thierry L. Bobanga, Célestin N. Nsibu, Georges L. Mvumbi, Pierrette Melin, Patrick De Mol, Marie-Pierre Hayette

Abstract

Malaria cases were estimated to 207 million in 2013. One of the problems of malaria control is the emergence and spread of Plasmodium falciparum strains that become resistant to almost all drugs available. Monitoring drug resistance is essential for early detection and subsequent prevention of the spread of drug resistance by timely changes of treatment policy. This review was performed to gather all data available on P. falciparum molecular resistance in DR Congo, as baseline for future assessments. The search for this review was undertaken using the electronic databases PubMed and Google Scholar using the terms "malaria", "Congo", "resistance", "molecular", "antimalarial", "efficacy". Articles were classified based on year of collecting, year of publication, sample size and characteristics, molecular markers analysed and polymorphisms detected. Thirteen articles were included and five genes have been analysed in these studies: pfcrt, pfdhps, pfdhfr, pfmdr1 and K13-propeller. The majority of studies included were not representative of the whole country. This systematic review demonstrates the lack of molecular resistance studies in DRC. Only 13 studies were identified in almost 15 years. The MOH must implement a national surveillance system for monitoring malaria drug resistance and this surveillance should be conducted frequently and country-representative.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Kenya 1 1%
Unknown 86 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 25%
Researcher 11 13%
Student > Postgraduate 8 9%
Student > Ph. D. Student 8 9%
Student > Bachelor 4 5%
Other 16 18%
Unknown 19 22%
Readers by discipline Count As %
Medicine and Dentistry 26 30%
Agricultural and Biological Sciences 13 15%
Biochemistry, Genetics and Molecular Biology 6 7%
Immunology and Microbiology 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 12 14%
Unknown 24 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2015.
All research outputs
#6,508,932
of 23,726,221 outputs
Outputs from Malaria Journal
#1,769
of 5,696 outputs
Outputs of similar age
#76,088
of 273,784 outputs
Outputs of similar age from Malaria Journal
#34
of 136 outputs
Altmetric has tracked 23,726,221 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 5,696 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,784 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 136 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.