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Nigella sativa fixed and essential oil modulates glutathione redox enzymes in potassium bromate induced oxidative stress

Overview of attention for article published in BMC Complementary Medicine and Therapies, September 2015
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  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

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8 X users

Citations

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47 Mendeley
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Title
Nigella sativa fixed and essential oil modulates glutathione redox enzymes in potassium bromate induced oxidative stress
Published in
BMC Complementary Medicine and Therapies, September 2015
DOI 10.1186/s12906-015-0853-7
Pubmed ID
Authors

Muhammad Tauseef Sultan, Masood Sadiq Butt, Roselina Karim, Waqas Ahmed, Ubedullah Kaka, Shakeel Ahmad, Saikat Dewanjee, Hawa ZE Jaafar, M. Zia-Ul-Haq

Abstract

Nigella sativa is an important component of several traditional herbal preparations in various countries. It finds its applications in improving overall health and boosting immunity. The current study evaluated the role of fixed and essential oil of Nigella sativa against potassium bromate induced oxidative stress with special reference to modulation of glutathione redox enzymes and myeloperoxidase. Animals; 30 rats (Sprague Dawley) were divided in three groups and oxidative stress was induced using mild dose of potassium bromate. The groups were on their respective diets (iso-caloric diets for a period of 56 days) i.e. control and two experimental diets containing N. sativa fixed (4 %) and essential (0.3 %) oils. The activities of enzymes involved in glutathione redox system and myeloperoxidase (MPO) were analyzed. The experimental diets modulated the activities of enzymes i.e. glutathione-S-transferase (GST), glutathione reductase (GR) and glutathione peroxidase (GPx) positively. Indices of antioxidant status like tocopherols and glutathione were in linear relationship with that of GPx, GR and GST (P < 0.01). MPO activities were in negative correlation with GST (P < 0.01) but positive correlation with some other parameters. Our results indicated that both Nigella sativa fixed and essential oil are effective in improving the antioxidant indices against potassium bromate induced oxidative stress.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 11%
Student > Ph. D. Student 5 11%
Student > Bachelor 5 11%
Student > Doctoral Student 5 11%
Student > Master 4 9%
Other 8 17%
Unknown 15 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 17%
Agricultural and Biological Sciences 8 17%
Medicine and Dentistry 3 6%
Engineering 2 4%
Immunology and Microbiology 2 4%
Other 4 9%
Unknown 20 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2022.
All research outputs
#7,055,623
of 25,159,758 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,108
of 3,934 outputs
Outputs of similar age
#78,480
of 279,119 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#23
of 87 outputs
Altmetric has tracked 25,159,758 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 3,934 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,119 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.