Title |
HiCPlotter integrates genomic data with interaction matrices
|
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Published in |
Genome Biology, September 2015
|
DOI | 10.1186/s13059-015-0767-1 |
Pubmed ID | |
Authors |
Kadir Caner Akdemir, Lynda Chin |
Abstract |
Metazoan genomic material is folded into stable non-randomly arranged chromosomal structures that are tightly associated with transcriptional regulation and DNA replication. Various factors including regulators of pluripotency, long non-coding RNAs, or the presence of architectural proteins have been implicated in regulation and assembly of the chromatin architecture. Therefore, comprehensive visualization of this multi-faceted structure is important to unravel the connections between nuclear architecture and transcriptional regulation. Here, we present an easy-to-use open-source visualization tool, HiCPlotter, to facilitate juxtaposition of Hi-C matrices with diverse genomic assay outputs, as well as to compare interaction matrices between various conditions. https://github.com/kcakdemir/HiCPlotter. |
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United Kingdom | 3 | 20% |
France | 2 | 13% |
India | 1 | 7% |
Belgium | 1 | 7% |
Unknown | 5 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 7 | 47% |
Members of the public | 7 | 47% |
Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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France | 3 | 2% |
Germany | 1 | <1% |
Portugal | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
Mexico | 1 | <1% |
Russia | 1 | <1% |
Spain | 1 | <1% |
Unknown | 126 | 93% |
Demographic breakdown
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Researcher | 39 | 29% |
Student > Ph. D. Student | 35 | 26% |
Student > Master | 13 | 10% |
Student > Doctoral Student | 10 | 7% |
Student > Bachelor | 6 | 4% |
Other | 14 | 10% |
Unknown | 19 | 14% |
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---|---|---|
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Biochemistry, Genetics and Molecular Biology | 49 | 36% |
Medicine and Dentistry | 6 | 4% |
Computer Science | 5 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | <1% |
Other | 2 | 1% |
Unknown | 21 | 15% |