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Rethinking urinary antibiotic breakpoints: analysis of urinary antibiotic concentrations to treat multidrug resistant organisms

Overview of attention for article published in BMC Research Notes, July 2018
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  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

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2 X users

Citations

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Readers on

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31 Mendeley
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Title
Rethinking urinary antibiotic breakpoints: analysis of urinary antibiotic concentrations to treat multidrug resistant organisms
Published in
BMC Research Notes, July 2018
DOI 10.1186/s13104-018-3599-8
Pubmed ID
Authors

Daniel B. Chastain, S. Travis King, Kayla R. Stover

Abstract

The present study analyzed whether renally eliminated antibiotics achieve sufficient urinary concentrations based on their pharmacokinetic/pharmacodynamic principles to effectively eradicate organisms deemed resistant by automated susceptibility testing. Lower median minimum inhibitory concentrations against enterobacteriaceae were noted for ceftriaxone, cefepime, and doripenem when comparing Etest® to Vitek®. All Pseudomonas aeruginosa isolates were susceptible to cefepime, ciprofloxacin, and doripenem with both susceptibility methods, but higher median minimum inhibitory concentrations were observed with Etest®. Urine concentrations/time profiles were calculated for standard doses of ceftriaxone, cefepime, doripenem, and ciprofloxacin. The data presented in the current study suggests high urine concentrations of antibiotics may effectively eradicate bacteria which were determined to be resistant per in vitro susceptibility testing.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 23%
Student > Ph. D. Student 4 13%
Student > Bachelor 2 6%
Professor > Associate Professor 2 6%
Student > Master 2 6%
Other 3 10%
Unknown 11 35%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 7 23%
Medicine and Dentistry 4 13%
Biochemistry, Genetics and Molecular Biology 2 6%
Engineering 2 6%
Environmental Science 1 3%
Other 4 13%
Unknown 11 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2021.
All research outputs
#15,797,338
of 24,077,033 outputs
Outputs from BMC Research Notes
#2,218
of 4,360 outputs
Outputs of similar age
#201,619
of 332,477 outputs
Outputs of similar age from BMC Research Notes
#66
of 154 outputs
Altmetric has tracked 24,077,033 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,360 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,477 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.