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The relationship between brain-derived neurotrophic factor and cognitive functions in alcohol-dependent patients: a preliminary study

Overview of attention for article published in Annals of General Psychiatry, September 2015
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Title
The relationship between brain-derived neurotrophic factor and cognitive functions in alcohol-dependent patients: a preliminary study
Published in
Annals of General Psychiatry, September 2015
DOI 10.1186/s12991-015-0065-z
Pubmed ID
Authors

Changwoo Han, Hwallip Bae, Sung-Doo Won, Sungwon Roh, Dai-Jin Kim

Abstract

As a neurotoxic substance, alcohol can induce neurodegenesis in the brain. Alcohol-dependent patients' cognitive functioning can be affected by chronic alcohol use. In addition, brain-derived neurotrophic factor (BDNF) is known to reflect the status of neuroadaptive changes. The purpose of this study was to investigate the relationship between cognitive functions and BDNF in alcohol-dependent patients. The subjects were 39 alcohol-dependent patients. BDNF was measured using an enzyme-linked immunosorbent assay kit. We examined clinical features and administered the Korean version of Alcohol Dependence Scale. We also used the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) to measure cognitive functioning. Then, we determined the relationships between BDNF and various parts of the CERAD. The performance of alcohol-dependent patients proved stable in most parts of the CERAD. Within the different parts of the CERAD, only Trail Making Test B correlated with BDNF. Trail Making Test specifically assesses executive functions. BDNF might play an important role in the detection of neurocognitive function among individuals with alcohol dependence.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 30 97%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 6 19%
Student > Bachelor 6 19%
Researcher 4 13%
Professor > Associate Professor 3 10%
Student > Ph. D. Student 2 6%
Other 6 19%
Unknown 4 13%
Readers by discipline Count As %
Medicine and Dentistry 11 35%
Psychology 8 26%
Biochemistry, Genetics and Molecular Biology 1 3%
Nursing and Health Professions 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 3 10%
Unknown 6 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 September 2015.
All research outputs
#14,825,907
of 22,829,083 outputs
Outputs from Annals of General Psychiatry
#267
of 510 outputs
Outputs of similar age
#151,658
of 274,809 outputs
Outputs of similar age from Annals of General Psychiatry
#7
of 14 outputs
Altmetric has tracked 22,829,083 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 510 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,809 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.