Title |
Occurrence of multidrug-resistant and ESBL-producing atypical enteropathogenic Escherichia coli in China
|
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Published in |
Gut Pathogens, February 2018
|
DOI | 10.1186/s13099-018-0234-0 |
Pubmed ID | |
Authors |
Yanmei Xu, Hui Sun, Xiangning Bai, Shanshan Fu, Ruyue Fan, Yanwen Xiong |
Abstract |
Atypical enteropathogenic Escherichia coli (aEPEC) is regarded as a globally emerging enteropathogen. aEPECs exhibit various level of resistance to a range of antibiotics, which is increasing alarmingly. The present study investigated the antimicrobial resistance of aEPEC isolates recovered from diarrheal patients, healthy carriers, animals, and raw meats. Among 267 aEPEC isolates, 146 (54.7%) were resistant to tetracycline, followed by ampicillin (49.4%), streptomycin (46.1%), and piperacillin (41.2%). Multidrug resistance (MDR) was detected in 128 (47.9%) isolates, and 40 MDR isolates were resistant to ≥ 10 antimicrobial agents. A total of 47 (17.6%) aEPEC isolates were identified as extended-spectrum β-lactamase (ESBL)-producers. The blaCTX-M-14 and blaCTX-M-15 genes were predominant among ESBL-producing isolates. This investigation depicted the occurrence of multidrug-resistant and ESBL-producing aEPEC isolates in China. The results suggested that it is necessary to continuously monitor the emergence and spread of MDR aEPEC. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 42 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 8 | 19% |
Student > Bachelor | 5 | 12% |
Researcher | 4 | 10% |
Student > Ph. D. Student | 4 | 10% |
Student > Doctoral Student | 3 | 7% |
Other | 7 | 17% |
Unknown | 11 | 26% |
Readers by discipline | Count | As % |
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Immunology and Microbiology | 8 | 19% |
Biochemistry, Genetics and Molecular Biology | 7 | 17% |
Medicine and Dentistry | 3 | 7% |
Nursing and Health Professions | 2 | 5% |
Engineering | 2 | 5% |
Other | 6 | 14% |
Unknown | 14 | 33% |