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Using mathematical models to understand metabolism, genes, and disease

Overview of attention for article published in BMC Biology, September 2015
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Title
Using mathematical models to understand metabolism, genes, and disease
Published in
BMC Biology, September 2015
DOI 10.1186/s12915-015-0189-2
Pubmed ID
Authors

H. Frederik Nijhout, Janet A. Best, Michael C. Reed

Abstract

Mathematical models are a useful tool for investigating a large number of questions in metabolism, genetics, and gene-environment interactions. A model based on the underlying biology and biochemistry is a platform for in silico biological experimentation that can reveal the causal chain of events that connect variation in one quantity to variation in another. We discuss how we construct such models, how we have used them to investigate homeostatic mechanisms, gene-environment interactions, and genotype-phenotype mapping, and how they can be used in precision and personalized medicine.

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X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Brazil 2 2%
Singapore 1 <1%
Unknown 106 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 23%
Researcher 23 21%
Student > Master 10 9%
Professor > Associate Professor 9 8%
Student > Bachelor 8 7%
Other 19 17%
Unknown 17 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 18%
Biochemistry, Genetics and Molecular Biology 17 15%
Medicine and Dentistry 11 10%
Engineering 8 7%
Mathematics 8 7%
Other 25 23%
Unknown 22 20%