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Early BCG vaccine to low-birth-weight infants and the effects on growth in the first year of life: a randomised controlled trial

Overview of attention for article published in BMC Pediatrics, September 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

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Title
Early BCG vaccine to low-birth-weight infants and the effects on growth in the first year of life: a randomised controlled trial
Published in
BMC Pediatrics, September 2015
DOI 10.1186/s12887-015-0452-2
Pubmed ID
Authors

Sofie Biering-Sørensen, Andreas Andersen, Henrik Ravn, Ivan Monterio, Peter Aaby, Christine Stabell Benn

Abstract

Randomised trials have shown that early Bacille Calmette-Guérin (BCG) vaccine reduces overall neonatal and infant mortality. However, no study has examined how BCG affects growth. We investigated the effect on infant growth of early BCG vaccine given to low-birth-weight (LBW) infants. Two-thousand three hundred forty-three LBW infants were randomly allocated 1:1 to "early BCG" (intervention group) or "late BCG" (current practice). Furthermore, a subgroup (N = 1717) were included in a two-by-two randomised trial in which they were additionally randomised 1:1 to vitamin A supplementation (VAS) or placebo. Anthropometric measurements were obtained 2, 6, and 12 months after enrolment. Overall there was no effect of early BCG on growth in the first year of life. The effect of early BCG on weight and mid-upper-arm circumference at 2 months tended to be beneficial among girls but not among boys (interaction between "early BCG" and sex: weight p = 0.03 and MUAC p = 0.04). This beneficial effect among girls was particularly seen among the largest infants weighing 2.0 kg or more at inclusion. Though BCG vaccination is not recommended to be given to LBW infants at birth in Guinea-Bissau, early BCG had no negative effect on infant growth and may have had a beneficial effect for girls. ClinicalTrials.gov (NCT00146302) .

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 18%
Student > Ph. D. Student 8 11%
Student > Master 7 10%
Student > Postgraduate 6 8%
Lecturer 2 3%
Other 11 15%
Unknown 26 36%
Readers by discipline Count As %
Medicine and Dentistry 18 25%
Nursing and Health Professions 9 12%
Immunology and Microbiology 5 7%
Social Sciences 3 4%
Agricultural and Biological Sciences 2 3%
Other 9 12%
Unknown 27 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2024.
All research outputs
#7,871,615
of 25,628,260 outputs
Outputs from BMC Pediatrics
#1,413
of 3,485 outputs
Outputs of similar age
#87,494
of 287,006 outputs
Outputs of similar age from BMC Pediatrics
#23
of 68 outputs
Altmetric has tracked 25,628,260 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 3,485 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,006 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.