Title |
A flexible framework for sparse simultaneous component based data integration
|
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Published in |
BMC Bioinformatics, November 2011
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DOI | 10.1186/1471-2105-12-448 |
Pubmed ID | |
Authors |
Katrijn Van Deun, Tom F Wilderjans, Robert A van den Berg, Anestis Antoniadis, Iven Van Mechelen |
Abstract |
High throughput data are complex and methods that reveal structure underlying the data are most useful. Principal component analysis, frequently implemented as a singular value decomposition, is a popular technique in this respect. Nowadays often the challenge is to reveal structure in several sources of information (e.g., transcriptomics, proteomics) that are available for the same biological entities under study. Simultaneous component methods are most promising in this respect. However, the interpretation of the principal and simultaneous components is often daunting because contributions of each of the biomolecules (transcripts, proteins) have to be taken into account. |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
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Portugal | 1 | 2% |
Germany | 1 | 2% |
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Demographic breakdown
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Researcher | 15 | 25% |
Other | 4 | 7% |
Professor > Associate Professor | 4 | 7% |
Student > Master | 2 | 3% |
Other | 5 | 8% |
Unknown | 10 | 17% |
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Psychology | 3 | 5% |
Other | 11 | 18% |
Unknown | 12 | 20% |