Title |
Mitral valve replacement complicated by iatrogenic left ventricular outflow obstruction and paravalvular leak: case report and review of literature
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Published in |
BMC Cardiovascular Disorders, October 2015
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DOI | 10.1186/s12872-015-0108-z |
Pubmed ID | |
Authors |
Justin Z. Lee, Kai R. Tey, Ahmad Mizyed, Charles T. Hennemeyer, Rajesh Janardhanan, Kapildeo Lotun |
Abstract |
Left ventricular outflow tract (LVOT) obstruction and paravalvular leak (PVL) are relatively uncommon, but are serious complications of prosthetic valve replacement. We present a case that displays the unique therapeutic challenges of treating a patient who developed both LVOT obstruction and mitral PVL after undergoing surgical aortic and mitral valve replacement (MVR). We also describe the use of alcohol septal ablation and albumin-glutaraldehyde (BioGlue) for septal ablation to percutaneously treat the patient's LVOT obstruction, followed by use of an Amplatzer vascular plug for percutaneous closure of an antero-medial mitral PVL associated with severe regurgitation. Percutaneous interventional management of these entities may be considered as an initial therapeutic option, especially in high-risk patients with significant morbidity and mortality of repeat surgical operations. |
X Demographics
Geographical breakdown
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 4 | 17% |
Researcher | 2 | 9% |
Student > Bachelor | 2 | 9% |
Student > Doctoral Student | 2 | 9% |
Other | 1 | 4% |
Other | 5 | 22% |
Unknown | 7 | 30% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 10 | 43% |
Nursing and Health Professions | 2 | 9% |
Mathematics | 1 | 4% |
Unspecified | 1 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Other | 1 | 4% |
Unknown | 7 | 30% |