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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Phyto-polyphenols as potential inhibitors of breast cancer metastasis
|
|---|---|
| Published in |
Molecular Medicine, June 2018
|
| DOI | 10.1186/s10020-018-0032-7 |
| Pubmed ID | |
| Authors |
Dimiter Avtanski, Leonid Poretsky |
| Abstract |
Breast cancer is the most common cancer among women as metastasis is currently the main cause of mortality. Breast cancer cells undergoing metastasis acquire resistance to death signals and increase of cellular motility and invasiveness.Plants are rich in polyphenolic compounds, many of them with known medicinal effects. Various phyto-polyphenols have also been demonstrated to suppress cancer growth. Their mechanism of action is usually pleiotropic as they target multiple signaling pathways regulating key cellular processes such as proliferation, apoptosis and differentiation. Importantly, some phyto- polyphenols show low level of toxicity to untransformed cells, but selective suppressing effects on cancer cells proliferation and differentiation.In this review, we summarize the current information about the mechanism of action of some phyto-polyphenols that have demonstrated anti-carcinogenic activities in vitro and in vivo. Gained knowledge of how these natural polyphenolic compounds work can give us a clue for the development of novel anti-metastatic agents. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 138 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 17 | 12% |
| Student > Ph. D. Student | 14 | 10% |
| Researcher | 14 | 10% |
| Student > Master | 13 | 9% |
| Student > Doctoral Student | 6 | 4% |
| Other | 20 | 14% |
| Unknown | 54 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 29 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 11% |
| Agricultural and Biological Sciences | 11 | 8% |
| Medicine and Dentistry | 10 | 7% |
| Immunology and Microbiology | 4 | 3% |
| Other | 14 | 10% |
| Unknown | 55 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2018.
All research outputs
#4,422,635
of 24,195,945 outputs
Outputs from Molecular Medicine
#175
of 1,211 outputs
Outputs of similar age
#82,183
of 334,088 outputs
Outputs of similar age from Molecular Medicine
#5
of 13 outputs
Altmetric has tracked 24,195,945 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,211 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,088 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.