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Upper gastrointestinal bleeding due to peptic ulcer disease is not associated with air pollution: a case-crossover study

Overview of attention for article published in BMC Gastroenterology, October 2015
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  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

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Title
Upper gastrointestinal bleeding due to peptic ulcer disease is not associated with air pollution: a case-crossover study
Published in
BMC Gastroenterology, October 2015
DOI 10.1186/s12876-015-0363-6
Pubmed ID
Authors

Samuel Quan, Hong Yang, Divine Tanyingoh, Paul J. Villeneuve, David M. Stieb, Markey Johnson, Robert Hilsden, Karen Madsen, Sander Veldhuyzen van Zanten, Kerri Novak, Eddy Lang, Subrata Ghosh, Gilaad G. Kaplan

Abstract

Recent studies have demonstrated an association between short-term elevations in air pollution and an increased risk of exacerbating gastrointestinal disease. The objective of the study was to evaluate if day-to-day increases in air pollution concentrations were positively associated with upper gastrointestinal bleeding (UGIB) secondary to peptic ulcer disease (PUD). A time-stratified case-crossover study design was used. Adults presenting to hospitals with their first UGIB secondary to PUD from 2004-2010 were identified using administrative databases from Calgary (n = 1374; discovery cohort) and Edmonton (n = 1159; replication cohort). Daily concentrations of ozone, nitrogen dioxide, sulfur dioxide, carbon monoxide, and particulate matter (PM10 and PM2.5) were estimated in these two cities. Conditional logistic regression models were employed, adjusting for temperature and humidity. Odds ratios (OR) with 95 % confidence intervals (CI) were expressed relative to an interquartile range increase in the concentration of each pollutant. No statistically significant associations were observed for any of the individual pollutants based on same-day, or 1-day lag effects within the Calgary discovery cohort. When the air pollution exposures were assessed as 3-, 5-, and 7-day averages, some pollutants were inversely associated with UGIB in the discovery cohort; for example, 5-day averages of nitrogen dioxide (OR = 0.68; 95 % CI: 0.53-0.88), and particulate matter <2.5 μm (OR = 0.75; 95 % CI: 0.61-0.90). However, these findings could not be reproduced in the replication cohort. Our findings suggest that short-term elevations in the level of ambient air pollutants does not increase the incidence of UGIB secondary to PUD.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 54 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 15%
Student > Master 6 11%
Student > Bachelor 5 9%
Professor > Associate Professor 5 9%
Student > Doctoral Student 4 7%
Other 9 16%
Unknown 18 33%
Readers by discipline Count As %
Medicine and Dentistry 18 33%
Environmental Science 6 11%
Agricultural and Biological Sciences 3 5%
Nursing and Health Professions 3 5%
Engineering 2 4%
Other 5 9%
Unknown 18 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2017.
All research outputs
#12,937,813
of 22,830,751 outputs
Outputs from BMC Gastroenterology
#584
of 1,745 outputs
Outputs of similar age
#124,134
of 279,406 outputs
Outputs of similar age from BMC Gastroenterology
#11
of 38 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,745 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,406 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.