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Coffee consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies

Overview of attention for article published in BMC Cancer, October 2015
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Title
Coffee consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies
Published in
BMC Cancer, October 2015
DOI 10.1186/s12885-015-1758-z
Pubmed ID
Authors

Liqing Li, Yong Gan, Chunmei Wu, Xianguo Qu, Gang Sun, Zuxun Lu

Abstract

Several observational studies suggest that coffee consumption may be associated with an increased risk of gastric cancer, but the results are inconsistent. We conducted a meta-analysis to evaluate the relationship of coffee consumption with gastric cancer risk and quantify the dose-response relationship between them. Relevant prospective studies were identified by a search of PubMed, Embase, and Web of Science to May 2015 and by reviewing the references of retrieved articles. Two independent reviewers extracted data and performed the quality assessment. A random-effects model was used to calculate the pooled risk estimates and 95 % confidence intervals (CI). The heterogeneity was assessed using the I (2) statistic. Publication bias was assessed by using funnel plot, the Begg test and the Egger test. Thirteen prospective cohort studies with 20 independent reports involving 3,368 patients with gastric cancer and 1,372,811 participants during a follow-up period ranging from 4.3-8 years were included. Compared with the lowest consumption level of coffee, the pooled relative risk (RR) was 1.13 (95 % CI: 0.94-1.35). The dose-response analysis indicated that, the RR of gastric cancer was 1.03 (95 % CI; 0.95-1.11) for per 3 cups/day of coffee consumption. Any nonlinear association of gastric cancer risk with coffee consumption was not found (P for nonlinearity = 0.68). Subgroup analyses indicated that the pooled RR for participants from the United States comparing the highest with the lowest coffee consumption was 1.36 (95 % CI, 1.06-1.75, I (2)  = 0 %). In addition, people with higher coffee consumption was associated with 25 % higher risk of gastric cancer in equal to or less than 10 years follow-up group (RR = 1.25; 95 % CI, 1.01-1.55, I (2)  = 0 %). Visual inspection of a funnel plot and the Begg's and the Egger's tests did not indicate evidence of publication bias. This meta-analysis does not support the hypothesis that coffee consumption is associated with the risk of gastric cancer. The increased risk of gastric cancer for participants from the United States and equal to or less than 10 years follow-up group associated with coffee consumption warrant further studies.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 2%
Unknown 64 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 18%
Student > Bachelor 9 14%
Student > Doctoral Student 5 8%
Researcher 4 6%
Professor > Associate Professor 4 6%
Other 15 23%
Unknown 16 25%
Readers by discipline Count As %
Medicine and Dentistry 16 25%
Agricultural and Biological Sciences 8 12%
Biochemistry, Genetics and Molecular Biology 7 11%
Sports and Recreations 2 3%
Engineering 2 3%
Other 6 9%
Unknown 24 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2019.
All research outputs
#15,348,897
of 22,830,751 outputs
Outputs from BMC Cancer
#4,112
of 8,306 outputs
Outputs of similar age
#166,164
of 283,771 outputs
Outputs of similar age from BMC Cancer
#104
of 233 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,306 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,771 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 233 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.