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Effects of zeolite supplementation on parameters of intestinal barrier integrity, inflammation, redoxbiology and performance in aerobically trained subjects

Overview of attention for article published in Journal of the International Society of Sports Nutrition, April 2022
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
38 X users
facebook
8 Facebook pages
video
3 YouTube creators

Citations

dimensions_citation
48 Dimensions

Readers on

mendeley
146 Mendeley
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Title
Effects of zeolite supplementation on parameters of intestinal barrier integrity, inflammation, redoxbiology and performance in aerobically trained subjects
Published in
Journal of the International Society of Sports Nutrition, April 2022
DOI 10.1186/s12970-015-0101-z
Pubmed ID
Authors

Manfred Lamprecht, Simon Bogner, Kurt Steinbauer, Burkhard Schuetz, Joachim F. Greilberger, Bettina Leber, Bernhard Wagner, Erwin Zinser, Thomas Petek, Sandra Wallner-Liebmann, Tanja Oberwinkler, Norbert Bachl, Gert Schippinger

Abstract

Zeolites are crystalline compounds with microporous structures of Si-tetrahedrons. In the gut, these silicates could act as adsorbents, ion-exchangers, catalysts, detergents or anti-diarrheic agents. This study evaluated whether zeolite supplementation affects biomarkers of intestinal wall permeability and parameters of oxidation and inflammation in aerobically trained individuals, and whether it could improve their performance. In a randomized, double-blinded, placebo controlled trial, 52 endurance trained men and women, similar in body fat, non-smokers, 20-50 years, received 1.85 g of zeolite per day for 12 weeks. Stool samples for determination of intestinal wall integrity biomarkers were collected. From blood, markers of redox biology, inflammation, and DNA damage were determined at the beginning and the end of the study. In addition, VO2max and maximum performance were evaluated at baseline and after 12 weeks of treatment. For statistical analyses a 2-factor ANOVA was used. At baseline both groups showed slightly increased stool zonulin concentrations above normal. After 12 weeks with zeolite zonulin was significantly (p < 0.05) decreased in the supplemented group. IL-10 increased tendentially (p < 0.1) in the zeolite group. There were no significant changes observed in the other measured parameters. Twelve weeks of zeolite supplementation exerted beneficial effects on intestinal wall integrity as indicated via decreased concentrations of the tight junction modulator zonulin. This was accompanied by mild anti-inflammatory effects in this cohort of aerobically trained subjects. Further research is needed to explore mechanistic explanations for the observations in this study.

X Demographics

X Demographics

The data shown below were collected from the profiles of 38 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Unknown 145 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 14%
Student > Master 20 14%
Student > Bachelor 19 13%
Student > Ph. D. Student 10 7%
Other 10 7%
Other 28 19%
Unknown 39 27%
Readers by discipline Count As %
Medicine and Dentistry 24 16%
Nursing and Health Professions 15 10%
Agricultural and Biological Sciences 11 8%
Sports and Recreations 11 8%
Biochemistry, Genetics and Molecular Biology 10 7%
Other 28 19%
Unknown 47 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 42. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2024.
All research outputs
#975,741
of 25,382,440 outputs
Outputs from Journal of the International Society of Sports Nutrition
#237
of 948 outputs
Outputs of similar age
#24,227
of 447,696 outputs
Outputs of similar age from Journal of the International Society of Sports Nutrition
#222
of 851 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 948 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 63.9. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,696 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 851 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.