Title |
Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study
|
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Published in |
BMC Pediatrics, November 2011
|
DOI | 10.1186/1471-2431-11-108 |
Pubmed ID | |
Authors |
Paola Di Carlo, Alessandra Casuccio, Amelia Romano, Daria Spicola, Lucina Titone, Nadia Caccamo, Francesco Dieli, Caterina Mammina, Elisabetta Pace, Mark Gjomarkaj, Mario Melis, Manlio Tolomeo |
Abstract |
Studies of the apoptosis mechanisms involved in the pathogenesis of tuberculosis have suggested that Mycobacterium tuberculosis can actively interfere with the apoptosis of infected cells. In vivo studies have been performed in adult populations but have not focused on this process in children. In the present study, we analyzed spontaneous T lymphocyte (PBT) apoptosis in the peripheral blood of children with central nervous system tuberculosis (CNS TB), before and after chemotherapy, and compared the results with healthy controls. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 32 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 25% |
Student > Master | 6 | 19% |
Professor | 4 | 13% |
Student > Bachelor | 2 | 6% |
Student > Ph. D. Student | 2 | 6% |
Other | 4 | 13% |
Unknown | 6 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 38% |
Immunology and Microbiology | 4 | 13% |
Biochemistry, Genetics and Molecular Biology | 3 | 9% |
Nursing and Health Professions | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 4 | 13% |
Unknown | 7 | 22% |