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The effect of breastfeeding on the risk of asthma in high-risk children: a case-control study in Shanghai, China

Overview of attention for article published in BMC Pregnancy and Childbirth, August 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

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2 blogs
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20 X users
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1 Facebook page

Citations

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11 Dimensions

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88 Mendeley
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Title
The effect of breastfeeding on the risk of asthma in high-risk children: a case-control study in Shanghai, China
Published in
BMC Pregnancy and Childbirth, August 2018
DOI 10.1186/s12884-018-1936-5
Pubmed ID
Authors

Xiaona Huo, Shuyuan Chu, Li Hua, Yixiao Bao, Li Du, Jian Xu, Jun Zhang

Abstract

Increasing evidence shows that antibiotic use in pregnancy may increase the risk of childhood asthma but epidemiologic studies are still limited and findings are inconsistent. Meanwhile, exclusive and prolonged breastfeeding may prevent children from allergic diseases. We aimed to assess the association between prenatal antibiotic use and the risk of childhood asthma, and explore whether breastfeeding modifies the risk. We conducted a case-control study in Shanghai, China, from June 2015 to January 2016. A total of 634 asthma cases and 864 controls aged 3-12 years were included. Multiple logistic regressions were used to estimate crude and adjusted odds ratios (aOR). The prevalence of antibiotic use in pregnancy in the cases and controls was 7.1 and 3.5%, respectively. A significant association between prenatal antibiotic use and childhood asthma was observed (aOR: 1.7, 95% CI: 1.0-2.9), particularly in boys (aOR: 2.2, 95% CI: 1.1-4.4) and children with family history of allergic disorders (aOR: 3.1, 95% CI: 1.2-8.4). However, this association existed only in children who were not breastfed exclusively in the first six months of life (aOR 2.6, 95% CI 1.3-5.1) but not in children who were exclusively breastfed (aOR 0.9, 95% CI 0.4-2.1). Likewise, exclusive breastfeeding also decreased the association between antibiotic use in pregnancy and asthma in boys and in children with family histories of allergic diseases. Antibiotic use in pregnancy was a risk factor for childhood asthma. However, this risk may be attenuated by exclusive breastfeeding in the first six months of life, especially among high-risk children.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 88 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 18%
Researcher 10 11%
Unspecified 5 6%
Other 5 6%
Student > Ph. D. Student 5 6%
Other 12 14%
Unknown 35 40%
Readers by discipline Count As %
Medicine and Dentistry 20 23%
Nursing and Health Professions 9 10%
Unspecified 5 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Biochemistry, Genetics and Molecular Biology 2 2%
Other 8 9%
Unknown 42 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 December 2018.
All research outputs
#1,519,225
of 25,189,292 outputs
Outputs from BMC Pregnancy and Childbirth
#340
of 4,703 outputs
Outputs of similar age
#31,197
of 339,785 outputs
Outputs of similar age from BMC Pregnancy and Childbirth
#7
of 87 outputs
Altmetric has tracked 25,189,292 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,703 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,785 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.