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Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of genes

Overview of attention for article published in BMC Medical Genomics, November 2011
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  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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1 X user
patent
1 patent

Citations

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22 Dimensions

Readers on

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45 Mendeley
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1 CiteULike
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Title
Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of genes
Published in
BMC Medical Genomics, November 2011
DOI 10.1186/1755-8794-4-80
Pubmed ID
Authors

Alejandra Rodriguez-Martinez, Emma-Leena Alarmo, Lilli Saarinen, Johanna Ketolainen, Kari Nousiainen, Sampsa Hautaniemi, Anne Kallioniemi

Abstract

Bone morphogenetic proteins (BMPs) are members of the TGF-beta superfamily of growth factors. They are known for their roles in regulation of osteogenesis and developmental processes and, in recent years, evidence has accumulated of their crucial functions in tumor biology. BMP4 and BMP7, in particular, have been implicated in breast cancer. However, little is known about BMP target genes in the context of tumor. We explored the effects of BMP4 and BMP7 treatment on global gene transcription in seven breast cancer cell lines during a 6-point time series, using a whole-genome oligo microarray. Data analysis included hierarchical clustering of differentially expressed genes, gene ontology enrichment analyses and model based clustering of temporal data.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
France 1 2%
Singapore 1 2%
Unknown 42 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 27%
Researcher 7 16%
Student > Doctoral Student 4 9%
Professor > Associate Professor 4 9%
Student > Master 4 9%
Other 8 18%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 42%
Medicine and Dentistry 8 18%
Biochemistry, Genetics and Molecular Biology 6 13%
Computer Science 2 4%
Engineering 2 4%
Other 0 0%
Unknown 8 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2023.
All research outputs
#7,676,433
of 24,657,405 outputs
Outputs from BMC Medical Genomics
#354
of 1,341 outputs
Outputs of similar age
#66,607
of 249,484 outputs
Outputs of similar age from BMC Medical Genomics
#2
of 7 outputs
Altmetric has tracked 24,657,405 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,341 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,484 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.