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Exhaled nitric oxide decreases after positive food‐allergen challenge

Overview of attention for article published in Clinical and Translational Allergy, November 2011
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Title
Exhaled nitric oxide decreases after positive food‐allergen challenge
Published in
Clinical and Translational Allergy, November 2011
DOI 10.1186/2045-7022-1-14
Pubmed ID
Authors

Avigael H Benhamou, Alice Koehli, Isabelle Rochat, Demet Inci, Alexander Moeller, Philip Taramarcaz, Roger P Lauener, Philippe A Eigenmann

Abstract

Exhaled nitric oxide (FeNO) is a well described marker of airway inflammation in asthma and is also known to increase after chronic exposure to inhaled allergens. It is not known whether monitoring FeNO could be useful during food challenges to detect early or subclinical reactions. Forty children aged 3 to 16 years undergoing an allergen-food challenge at two centres were prospectively recruited for this study. FeNO was assessed before and repeatedly after the food-challenge. Data were obtained from a total of 53 challenges (16 positive, 37 negative) and were compared between the two groups. Half of the patients with a positive food challenge exhibited clinical upper respiratory symptoms. The FeNO significantly decreased in 7 of 16 patients with a positive challenge test within 60 to 90 minutes after the first symptoms of an allergic reaction. Our results show a significant decrease in FeNO after a positive food challenge suggesting involvement of the lower airways despite absence of clinical and functional changes of lower airways. Prospective blinded studies are needed to confirm these results.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 25%
Student > Doctoral Student 2 17%
Professor > Associate Professor 2 17%
Student > Master 2 17%
Lecturer 1 8%
Other 0 0%
Unknown 2 17%
Readers by discipline Count As %
Medicine and Dentistry 4 33%
Environmental Science 2 17%
Psychology 2 17%
Nursing and Health Professions 1 8%
Agricultural and Biological Sciences 1 8%
Other 0 0%
Unknown 2 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2011.
All research outputs
#19,944,994
of 25,374,647 outputs
Outputs from Clinical and Translational Allergy
#665
of 756 outputs
Outputs of similar age
#200,178
of 246,489 outputs
Outputs of similar age from Clinical and Translational Allergy
#11
of 11 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 756 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.