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Frequency and distribution of mixed Plasmodiumfalciparum-vivax infections in French Guiana between 2000 and 2008

Overview of attention for article published in Malaria Journal, November 2015
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Title
Frequency and distribution of mixed Plasmodiumfalciparum-vivax infections in French Guiana between 2000 and 2008
Published in
Malaria Journal, November 2015
DOI 10.1186/s12936-015-0971-1
Pubmed ID
Authors

Marine Ginouves, Vincent Veron, Lise Musset, Eric Legrand, Aurélia Stefani, Ghislaine Prevot, Magalie Demar, Félix Djossou, Paul Brousse, Mathieu Nacher, Bernard Carme

Abstract

The two main plasmodial species in French Guiana are Plasmodium vivax and Plasmodium falciparum whose respective prevalence influences the frequency of mixed plasmodial infections. The accuracy of their diagnosis is influenced by the sensitivity of the method used, whereas neither microscopy nor rapid diagnostic tests allow a satisfactory evaluation of mixed plasmodial infections. In the present study, the frequency of mixed infections in different part of French Guiana was determined using real time PCR, a sensitive and specific technique. From 400 cases of malaria initially diagnosed by microscopy, real time PCR showed that 10.75 % of the cases were mixed infections. Their prevalence varied considerably between geographical areas. The presence, in equivalent proportions, of the two plasmodial species in eastern French Guiana was associated with a much higher prevalence of mixed plasmodial infections than in western French Guiana, where the majority of the population was Duffy negative and thus resistant to vivax malaria. Clinicians must be more vigilant regarding mixed infections in co-endemic P. falciparum/P. vivax areas, in order to deliver optimal care for patients suffering from malaria. This may involve the use of rapid diagnostic tests capable of detecting mixed infections or low density single infections. This is important as French Guiana moves towards malaria elimination.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 19%
Student > Bachelor 6 14%
Student > Ph. D. Student 5 12%
Researcher 4 10%
Lecturer > Senior Lecturer 2 5%
Other 6 14%
Unknown 11 26%
Readers by discipline Count As %
Medicine and Dentistry 11 26%
Agricultural and Biological Sciences 7 17%
Biochemistry, Genetics and Molecular Biology 3 7%
Nursing and Health Professions 2 5%
Immunology and Microbiology 2 5%
Other 4 10%
Unknown 13 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2015.
All research outputs
#19,162,324
of 24,400,706 outputs
Outputs from Malaria Journal
#5,112
of 5,827 outputs
Outputs of similar age
#195,594
of 287,977 outputs
Outputs of similar age from Malaria Journal
#125
of 157 outputs
Altmetric has tracked 24,400,706 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,827 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
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We're also able to compare this research output to 157 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.