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Treatment of patients with sepsis in a closed intensive care unit is associated with improved survival: a nationwide observational study in Japan

Overview of attention for article published in Journal of Intensive Care, September 2018
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

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2 news outlets
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29 X users
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1 Facebook page

Citations

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19 Dimensions

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24 Mendeley
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Title
Treatment of patients with sepsis in a closed intensive care unit is associated with improved survival: a nationwide observational study in Japan
Published in
Journal of Intensive Care, September 2018
DOI 10.1186/s40560-018-0322-8
Pubmed ID
Authors

Takayuki Ogura, Yoshihiko Nakamura, Kunihiko Takahashi, Kazuki Nishida, Daisuke Kobashi, Shigeyuki Matsui

Abstract

The aim of this study is to investigate the association between treatment in a closed ICU and survival at discharge in patients with sepsis. This is a post hoc analysis utilizing data from the Japan Septic Disseminated Intravascular Coagulation study, including data from patients with sepsis from 2011 to 2013. Multiple logistic regression analysis was used to estimate the association between ICU policy and survival at discharge, and propensity score matching analysis was performed including the same covariates as a sensitivity analysis. Multiple linear regression analysis for the length of ICU stay in surviving patients was also performed with adjustments for the same covariates. Two thousand four hundred ninety-five patients were analyzed. The median Acute Physiology and Chronic Health Evaluation (APACHE) II score was 22 [17-29], the median Sequential Organ Failure Assessment (SOFA) score was 9 [7-12], and the overall mortality was 33%. There were 979 patients treated in 17 open ICUs and 1516 patients in 18 closed ICUs. In comparison, the APACHE II score and SOFA scores were significantly higher in patients in closed ICUs (closed vs open = 23 [18-29] vs 21 [16-28]; p < .001, 9 [7-13] vs 9 [6-12]; p = 0.004). There was no difference in the unadjusted mortality (closed vs open; 33.1% vs 33.2%), but in multiple logistic regression analysis, treatment in a closed ICU is significantly associated with survival at discharge (odds ratio = 1.59, 95% CI [1.276-1.827], p = .001). The sensitivity analysis (702 pairs of the matching) showed a significantly higher survival rate in the closed ICU (71.8% vs 65.2%, p = 0.011). The length of ICU stay of patients in closed ICUs was significantly shorter (20% less). This Japanese nationwide analysis of patients with sepsis shows a significant association between treatment in a closed ICU and survival at discharge, and a 20% decrease in ICU stay.

X Demographics

X Demographics

The data shown below were collected from the profiles of 29 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 13%
Student > Doctoral Student 2 8%
Professor 2 8%
Student > Postgraduate 2 8%
Student > Ph. D. Student 2 8%
Other 3 13%
Unknown 10 42%
Readers by discipline Count As %
Medicine and Dentistry 10 42%
Nursing and Health Professions 1 4%
Unspecified 1 4%
Neuroscience 1 4%
Design 1 4%
Other 0 0%
Unknown 10 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2023.
All research outputs
#1,154,285
of 25,067,172 outputs
Outputs from Journal of Intensive Care
#52
of 565 outputs
Outputs of similar age
#24,363
of 341,240 outputs
Outputs of similar age from Journal of Intensive Care
#3
of 22 outputs
Altmetric has tracked 25,067,172 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 565 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,240 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.