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Quantitative real-time PCR assisted cell counting (qPACC) for epigenetic - based immune cell quantification in blood and tissue

Overview of attention for article published in Journal for Immunotherapy of Cancer, November 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

twitter
4 tweeters
patent
2 patents

Citations

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7 Dimensions

Readers on

mendeley
36 Mendeley
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Title
Quantitative real-time PCR assisted cell counting (qPACC) for epigenetic - based immune cell quantification in blood and tissue
Published in
Journal for Immunotherapy of Cancer, November 2015
DOI 10.1186/s40425-015-0087-8
Pubmed ID
Authors

Thomas Oliver Kleen, Jianda Yuan

Abstract

A novel form of immune cell quantification in blood and tissue is described using epigenetic - based, quantitative real-time PCR assisted cell counting (qPACC). The methylation status of the chromatin structure of either actively expressed or silenced genes is the basis of the epigenetic-based cell identification and quantification technology. Discovery of cell type specific removal of methyl groups (demethylation) from the 5'-carbon of the cytosine base in the dinucleotide cytosine phosphate guanine permits precise and robust quantification of immune cells from only small amounts of human blood or tissue samples. These epigenetic biomarkers located on genomic DNA are stably associated with a cell type of interest.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 39%
Student > Ph. D. Student 5 14%
Student > Master 2 6%
Other 2 6%
Professor 1 3%
Other 3 8%
Unknown 9 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 25%
Immunology and Microbiology 7 19%
Agricultural and Biological Sciences 4 11%
Engineering 2 6%
Medicine and Dentistry 1 3%
Other 3 8%
Unknown 10 28%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2020.
All research outputs
#4,394,930
of 17,921,525 outputs
Outputs from Journal for Immunotherapy of Cancer
#742
of 1,839 outputs
Outputs of similar age
#83,813
of 370,261 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#24
of 107 outputs
Altmetric has tracked 17,921,525 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,839 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 370,261 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 107 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.