Title |
Computerized tomography based tumor-thickness measurement is useful to predict postoperative pathological tumor thickness in oral tongue squamous cell carcinoma
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Published in |
Journal of Otolaryngology - Head & Neck Surgery, November 2015
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DOI | 10.1186/s40463-015-0089-z |
Pubmed ID | |
Authors |
J. Madana, Frederick Laliberté, Grégoire B. Morand, Deeke Yolmo, Martin J. Black, Alex M. Mlynarek, Michael P. Hier |
Abstract |
Tumor thickness has been shown in oral tongue squamous cell carcinoma (OTSCC) to be a predictor of cervical metastasis. The postoperative histological measurement is certainly the most accurate, but it would be of clinical interest to gain this information prior to treatment planning. This retrospective study aimed to compare the tumor thickness measurement between preoperative, CT scan, and surgical specimens . We retrospectively included 116 OTSCC patients between 2001 and 2013. Thickness was measured on computer tomography imaging and again surgical specimens. The median age was 66 years. 62.8 % of patients were smokers with a mean of 31.4 pack-years. Positive nodal disease was reported in 41.2 %. Mean follow-up time was 33.1 months. The correlation between CT scan-based tumor thickness and surgical specimens based thickness was significant (Spearman rho = 0.755, P < 0.001). Tumor thickness assessed by CT scan may provide an accurate estimation of true thickness and can be used in treatment planning. |
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Unknown | 1 | 100% |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 4 | 20% |
Student > Master | 3 | 15% |
Student > Bachelor | 2 | 10% |
Researcher | 2 | 10% |
Student > Ph. D. Student | 2 | 10% |
Other | 4 | 20% |
Unknown | 3 | 15% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 75% |
Materials Science | 1 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Unknown | 3 | 15% |