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Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage

Overview of attention for article published in Journal of Neuroinflammation, December 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

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1 news outlet
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3 X users

Citations

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56 Dimensions

Readers on

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65 Mendeley
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Title
Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage
Published in
Journal of Neuroinflammation, December 2015
DOI 10.1186/s12974-015-0445-y
Pubmed ID
Authors

Gregory Scott, Peter J. Hellyer, Anil F. Ramlackhansingh, David J. Brooks, Paul M. Matthews, David J. Sharp

Abstract

Traumatic brain injury can trigger chronic neuroinflammation, which may predispose to neurodegeneration. Animal models and human pathological studies demonstrate persistent inflammation in the thalamus associated with axonal injury, but this relationship has never been shown in vivo. Using [(11)C]-PK11195 positron emission tomography, a marker of microglial activation, we previously demonstrated thalamic inflammation up to 17 years after traumatic brain injury. Here, we use diffusion MRI to estimate axonal injury and show that thalamic inflammation is correlated with thalamo-cortical tract damage. These findings support a link between axonal damage and persistent inflammation after brain injury.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 64 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 23%
Researcher 10 15%
Student > Bachelor 6 9%
Student > Master 6 9%
Student > Doctoral Student 5 8%
Other 12 18%
Unknown 11 17%
Readers by discipline Count As %
Neuroscience 20 31%
Medicine and Dentistry 8 12%
Psychology 6 9%
Biochemistry, Genetics and Molecular Biology 4 6%
Engineering 3 5%
Other 9 14%
Unknown 15 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2015.
All research outputs
#3,080,981
of 25,374,917 outputs
Outputs from Journal of Neuroinflammation
#480
of 2,951 outputs
Outputs of similar age
#48,449
of 395,421 outputs
Outputs of similar age from Journal of Neuroinflammation
#10
of 57 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,951 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,421 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.