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The HOPE fixation technique - a promising alternative to common prostate cancer biobanking approaches

Overview of attention for article published in BMC Cancer, December 2011
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Mentioned by

twitter
2 tweeters

Citations

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23 Dimensions

Readers on

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36 Mendeley
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Title
The HOPE fixation technique - a promising alternative to common prostate cancer biobanking approaches
Published in
BMC Cancer, December 2011
DOI 10.1186/1471-2407-11-511
Pubmed ID
Authors

Martin Braun, Roopika Menon, Pavel Nikolov, Robert Kirsten, Karen Petersen, David Schilling, Christina Schott, Sibylle Gündisch, Falko Fend, Karl-Friedrich Becker, Sven Perner

Abstract

The availability of well-annotated prostate tissue samples through biobanks is key for research. Whereas fresh-frozen tissue is well suited for a broad spectrum of molecular analyses, its storage and handling is complex and cost-intensive. Formalin-fixed paraffin-embedded specimens (FFPE) are easy to handle and economic to store, but their applicability for molecular methods is restricted. The recently introduced Hepes-glutamic acid-buffer mediated Organic solvent Protection Effect (HOPE) is a promising alternative, which might have the potential to unite the benefits of FFPE and fresh-frozen specimen. Aim of the study was to compare HOPE-fixed, FFPE and fresh-frozen bio-specimens for their accessibility for diagnostic and research purposes.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Netherlands 1 3%
Unknown 34 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 17%
Student > Bachelor 6 17%
Student > Ph. D. Student 5 14%
Student > Postgraduate 3 8%
Professor > Associate Professor 3 8%
Other 8 22%
Unknown 5 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 39%
Medicine and Dentistry 7 19%
Biochemistry, Genetics and Molecular Biology 4 11%
Nursing and Health Professions 1 3%
Arts and Humanities 1 3%
Other 2 6%
Unknown 7 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2020.
All research outputs
#15,293,096
of 19,770,032 outputs
Outputs from BMC Cancer
#4,044
of 7,093 outputs
Outputs of similar age
#180,830
of 237,351 outputs
Outputs of similar age from BMC Cancer
#181
of 292 outputs
Altmetric has tracked 19,770,032 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,093 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,351 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 292 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.